Elevated IgM levels as a marker for a unique phenotype in patients with Ataxia telangiectasia

BACKGROUND: Ataxia telangiectasia (AT) is a rare, multi-systemic, genetic disorder. Mutations in the ATM gene cause dysfunction in cell-cycle, apoptosis and V (D) J recombination leading to neurodegeneration, cellular, humoral immunodeficiencies and predisposition to malignancies. Previous studies h...

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Detalles Bibliográficos
Autores principales: Krauthammer, Alexander, Lahad, Avishay, Goldberg, Lior, Sarouk, Ifat, Weiss, Batia, Somech, Raz, Soudack, Michalle, Pessach, Itai M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987459/
https://www.ncbi.nlm.nih.gov/pubmed/29866155
http://dx.doi.org/10.1186/s12887-018-1156-1

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