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Targeted intracerebral delivery of the anti-inflammatory cytokine IL13 promotes alternative activation of both microglia and macrophages after stroke

BACKGROUND: Subtle adjustment of the activation status of CNS resident microglia and peripheral macrophages, to promote their neuroprotective and neuroregenerative functions, may facilitate research towards curing neurodegenerative disorders. In the present study, we investigated whether targeted in...

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Detalles Bibliográficos
Autores principales: Hamzei Taj, Somayyeh, Le Blon, Debbie, Hoornaert, Chloé, Daans, Jasmijn, Quarta, Alessandra, Praet, Jelle, Van der Linden, Annemie, Ponsaerts, Peter, Hoehn, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987479/
https://www.ncbi.nlm.nih.gov/pubmed/29866203
http://dx.doi.org/10.1186/s12974-018-1212-7