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Co-aggregation of pro-inflammatory S100A9 with α-synuclein in Parkinson’s disease: ex vivo and in vitro studies
BACKGROUND: Chronic neuroinflammation is a hallmark of Parkinson’s disease (PD) pathophysiology, associated with increased levels of pro-inflammatory factors in PD brain tissues. The pro-inflammatory mediator and highly amyloidogenic protein S100A9 is involved in the amyloid-neuroinflammatory cascad...
Autores principales: | Horvath, Istvan, Iashchishyn, Igor A., Moskalenko, Roman A., Wang, Chao, Wärmländer, Sebastian K. T. S., Wallin, Cecilia, Gräslund, Astrid, Kovacs, Gabor G., Morozova-Roche, Ludmilla A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987543/ https://www.ncbi.nlm.nih.gov/pubmed/29866153 http://dx.doi.org/10.1186/s12974-018-1210-9 |
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