Elimination of intravascular thrombi prevents early mortality and reduces gliosis in hyper-inflammatory experimental cerebral malaria

BACKGROUND: Cerebral malaria (CM) is the most lethal outcome of Plasmodium infection. There are clear correlations between expression of inflammatory cytokines, severe coagulopathies, and mortality in human CM. However, the mechanisms intertwining the coagulation and inflammation pathways, and their...

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Detalles Bibliográficos
Autores principales: Wilson, Kyle D., Ochoa, Lorenzo F., Solomon, Olivia D., Pal, Rahul, Cardona, Sandra M., Carpio, Victor H., Keiser, Philip H., Cardona, Astrid E., Vargas, Gracie, Stephens, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987620/
https://www.ncbi.nlm.nih.gov/pubmed/29866139
http://dx.doi.org/10.1186/s12974-018-1207-4

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