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Long non-coding RNA UBE2CP3 enhances HCC cell secretion of VEGFA and promotes angiogenesis by activating ERK1/2/HIF-1α/VEGFA signalling in hepatocellular carcinoma

BACKGROUND: Angiogenesis is considered as an important process in the development of malignancies and is associated with cancer progression and metastasis. Hepatocellular carcinoma (HCC) is the most common primary tumor of the liver and is recognized as a typical angiogenic tumor. Thus, it is of gre...

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Detalles Bibliográficos
Autores principales: Lin, Jinduan, Cao, Shunwang, Wang, Yu, Hu, Yanwei, Liu, Hongwei, Li, Jiehua, Chen, Jing, Li, Pan, Liu, Jumei, Wang, Qian, Zheng, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987644/
https://www.ncbi.nlm.nih.gov/pubmed/29866133
http://dx.doi.org/10.1186/s13046-018-0727-1