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Combination therapy with protein kinase inhibitor H89 and Tetrandrine elicits enhanced synergistic antitumor efficacy

BACKGROUND: Tetrandrine, a bisbenzylisoquinoline alkaloid that was isolated from the medicinal plant Stephania tetrandrine S. Moore, was recently identified as a novel chemotherapy drug. Tetrandrine exhibited a potential antitumor effect on multiple types of cancer. Notably, an enhanced therapeutic...

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Detalles Bibliográficos
Autores principales: Yu, Man, Liu, Ting, Chen, Yicheng, Li, Yafang, Li, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987653/
https://www.ncbi.nlm.nih.gov/pubmed/29866132
http://dx.doi.org/10.1186/s13046-018-0779-2