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Anxiety in women - a Swedish national three-generational cohort study

BACKGROUND: Findings from animal and human studies indicate that anxiety and stress have a negative influence on the child and mother. The aim of this study was to explore the risk for having an anxiety diagnosis and the impact of the diagnosis in a three generational perspective. METHODS: The infor...

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Autores principales: Sydsjö, Gunilla, Agnafors, Sara, Bladh, Marie, Josefsson, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987656/
https://www.ncbi.nlm.nih.gov/pubmed/29866128
http://dx.doi.org/10.1186/s12888-018-1712-0
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author Sydsjö, Gunilla
Agnafors, Sara
Bladh, Marie
Josefsson, Ann
author_facet Sydsjö, Gunilla
Agnafors, Sara
Bladh, Marie
Josefsson, Ann
author_sort Sydsjö, Gunilla
collection PubMed
description BACKGROUND: Findings from animal and human studies indicate that anxiety and stress have a negative influence on the child and mother. The aim of this study was to explore the risk for having an anxiety diagnosis and the impact of the diagnosis in a three generational perspective. METHODS: The information was retrieved from Swedish population-based registries. All women who gave birth between 1973 and 1977 (n 169,782), their daughters (n 244,152), and subsequently also the offspring of the daughters (n 381,953) were followed until 2013. RESULTS: We found that 4% of the mothers and 6% of the grandmothers had been diagnosed with anxiety. Women who had mothers with an anxiety disorder were more than twice as likely to have an anxiety disorder themselves compared to all other women (OR = 2.20, 95% CI = 2.04–2.30). In the third generation, the children born to mothers with an anxiety disorder, the odds ratio of being diagnosed with anxiety was more than twice as high than for the rest of the population (OR = 2.54, 95% CI = 2.01–3.20). If both the mother and the grandmother had had an anxiety disorder the odds ratio for the child having a diagnosis of anxiety was three times higher (OR = 3.11, 95% CI = 2.04–4.75). Anxiety diagnosis in the two previous generations also increased the likelihood of the child having either more than two inpatient visits or more than 10 outpatient visits (OR = 2.64, 95% CI = 2.40–2.91 and OR = 2.21, 95% CI = 2.01–2.43, respectively). CONCLUSIONS: The intergenerational effect on anxiety is high. In order to minimize the risk for further transmission of anxiety disorders, increased awareness and generous use of effective treatment regimes might be of importance.
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spelling pubmed-59876562018-06-20 Anxiety in women - a Swedish national three-generational cohort study Sydsjö, Gunilla Agnafors, Sara Bladh, Marie Josefsson, Ann BMC Psychiatry Research Article BACKGROUND: Findings from animal and human studies indicate that anxiety and stress have a negative influence on the child and mother. The aim of this study was to explore the risk for having an anxiety diagnosis and the impact of the diagnosis in a three generational perspective. METHODS: The information was retrieved from Swedish population-based registries. All women who gave birth between 1973 and 1977 (n 169,782), their daughters (n 244,152), and subsequently also the offspring of the daughters (n 381,953) were followed until 2013. RESULTS: We found that 4% of the mothers and 6% of the grandmothers had been diagnosed with anxiety. Women who had mothers with an anxiety disorder were more than twice as likely to have an anxiety disorder themselves compared to all other women (OR = 2.20, 95% CI = 2.04–2.30). In the third generation, the children born to mothers with an anxiety disorder, the odds ratio of being diagnosed with anxiety was more than twice as high than for the rest of the population (OR = 2.54, 95% CI = 2.01–3.20). If both the mother and the grandmother had had an anxiety disorder the odds ratio for the child having a diagnosis of anxiety was three times higher (OR = 3.11, 95% CI = 2.04–4.75). Anxiety diagnosis in the two previous generations also increased the likelihood of the child having either more than two inpatient visits or more than 10 outpatient visits (OR = 2.64, 95% CI = 2.40–2.91 and OR = 2.21, 95% CI = 2.01–2.43, respectively). CONCLUSIONS: The intergenerational effect on anxiety is high. In order to minimize the risk for further transmission of anxiety disorders, increased awareness and generous use of effective treatment regimes might be of importance. BioMed Central 2018-06-04 /pmc/articles/PMC5987656/ /pubmed/29866128 http://dx.doi.org/10.1186/s12888-018-1712-0 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Sydsjö, Gunilla
Agnafors, Sara
Bladh, Marie
Josefsson, Ann
Anxiety in women - a Swedish national three-generational cohort study
title Anxiety in women - a Swedish national three-generational cohort study
title_full Anxiety in women - a Swedish national three-generational cohort study
title_fullStr Anxiety in women - a Swedish national three-generational cohort study
title_full_unstemmed Anxiety in women - a Swedish national three-generational cohort study
title_short Anxiety in women - a Swedish national three-generational cohort study
title_sort anxiety in women - a swedish national three-generational cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987656/
https://www.ncbi.nlm.nih.gov/pubmed/29866128
http://dx.doi.org/10.1186/s12888-018-1712-0
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