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Intraperitoneal injection of the SIRT1 activator SRT1720 attenuates the progression of experimental osteoarthritis in mice

OBJECTIVES: This study aimed to examine the effects of SRT1720, a potent SIRT1 activator, on osteoarthritis (OA) progression using an experimental OA model. METHODS: Osteoarthritis was surgically induced by destabilization of the medial meniscus in eight-week-old C57BL/6 male mice. SRT1720 was admin...

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Detalles Bibliográficos
Autores principales:	Nishida, K., Matsushita, T., Takayama, K., Tanaka, T., Miyaji, N., Ibaraki, K., Araki, D., Kanzaki, N., Matsumoto, T., Kuroda, R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987681/ https://www.ncbi.nlm.nih.gov/pubmed/29922443 http://dx.doi.org/10.1302/2046-3758.73.BJR-2017-0227.R1

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