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Use of integrative epigenetic and mRNA expression analyses to identify significantly changed genes and functional pathways in osteoarthritic cartilage

AIM: Osteoarthritis (OA) is caused by complex interactions between genetic and environmental factors. Epigenetic mechanisms control the expression of genes and are likely to regulate the OA transcriptome. We performed integrative genomic analyses to define methylation-gene expression relationships i...

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Detalles Bibliográficos
Autores principales:	He, A., Ning, Y., Wen, Y., Cai, Y., Xu, K., Han, J., Liu, L., Du, Y., Liang, X., Li, P., Fan, Q., Hao, J., Wang, X., Guo, X., Ma, T., Zhang, F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987683/ https://www.ncbi.nlm.nih.gov/pubmed/29922454 http://dx.doi.org/10.1302/2046-3758.75.BJR-2017-0284.R1

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