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Autophagy regulates testosterone synthesis by facilitating cholesterol uptake in Leydig cells
Testosterone is indispensable for sexual development and maintaining male characteristics, and deficiency of this hormone results in primary or late-onset hypogonadism (LOH). Testosterone is primarily produced in Leydig cells, where autophagy has been reported to be extremely active. However, the fu...
Autores principales: | Gao, Fengyi, Li, Guoping, Liu, Chao, Gao, Hui, Wang, Hao, Liu, Weixiao, Chen, Min, Shang, Yongliang, Wang, Lina, Shi, Jian, Xia, Wenlong, Jiao, Jianwei, Gao, Fei, Li, Jian, Chen, Liang, Li, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987723/ https://www.ncbi.nlm.nih.gov/pubmed/29618492 http://dx.doi.org/10.1083/jcb.201710078 |
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