SAC-1 ensures epithelial endocytic recycling by restricting ARF-6 activity

Arf6/ARF-6 is a crucial regulator of the endosomal phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) pool in endocytic recycling. To further characterize ARF-6 regulation, we performed an ARF-6 interactor screen in Caenorhabditis elegans and identified SAC-1, the homologue of the phosphoinositide ph...

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Detalles Bibliográficos
Autores principales: Chen, Dan, Yang, Chao, Liu, Sha, Hang, Weijian, Wang, Xianghong, Chen, Juan, Shi, Anbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987724/
https://www.ncbi.nlm.nih.gov/pubmed/29563216
http://dx.doi.org/10.1083/jcb.201711065

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