Cargando…

Education and myopia: assessing the direction of causality by mendelian randomisation

OBJECTIVES: To determine whether more years spent in education is a causal risk factor for myopia, or whether myopia is a causal risk factor for more years in education. DESIGN: Bidirectional, two sample mendelian randomisation study. SETTING: Publically available genetic data from two consortiums a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mountjoy, Edward, Davies, Neil M, Plotnikov, Denis, Smith, George Davey, Rodriguez, Santiago, Williams, Cathy E, Guggenheim, Jeremy A, Atan, Denize
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group Ltd. 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987847/ https://www.ncbi.nlm.nih.gov/pubmed/29875094 http://dx.doi.org/10.1136/bmj.k2022

Ejemplares similares

Effect of Education on Myopia: Evidence from the United Kingdom ROSLA 1972 Reform
por: Plotnikov, Denis, et al.
Publicado: (2020)

Hyperopia Is Not Causally Associated With a Major Deficit in Educational Attainment
por: Plotnikov, Denis, et al.
Publicado: (2021)

Time Spent Outdoors Partly Accounts for the Effect of Education on Myopia
por: Clark, Rosie, et al.
Publicado: (2023)

Education and myopia: assessing the direction of causality by mendelian randomisation
Publicado: (2018)

Association Between Polygenic Risk Score and Risk of Myopia
por: Ghorbani Mojarrad, Neema, et al.
Publicado: (2019)

A commonly occurring genetic variant within the NPLOC4–TSPAN10–PDE6G gene cluster is associated with the risk of strabismus
por: Plotnikov, Denis, et al.
Publicado: (2019)

Novel Myopia Genes and Pathways Identified From Syndromic Forms of Myopia
por: Flitcroft, D. Ian, et al.
Publicado: (2018)

Non-additive (dominance) effects of genetic variants associated with refractive error and myopia
por: Pozarickij, Alfred, et al.
Publicado: (2020)

Cigarette smoking and personality: interrogating causality using Mendelian randomisation
por: Sallis, Hannah M., et al.
Publicado: (2019)

Time Outdoors at Specific Ages During Early Childhood and the Risk of Incident Myopia
por: Shah, Rupal L., et al.
Publicado: (2017)

A comparative analysis of rod bipolar cell transcriptomes identifies novel genes implicated in night vision
por: Woods, Sasha M., et al.
Publicado: (2018)

High Blood Pressure and Intraocular Pressure: A Mendelian Randomization Study
por: Plotnikov, Denis, et al.
Publicado: (2022)

USING MENDELIAN RANDOMISATION TO INFER CAUSALITY IN DEPRESSION AND ANXIETY RESEARCH
por: Gage, Suzanne H, et al.
Publicado: (2014)

Mendelian Randomization analysis of the causal effect of adiposity on hospital costs
por: Dixon, Padraig, et al.
Publicado: (2020)

Educational inequality in multimorbidity: causality and causal pathways. A mendelian randomisation study in UK Biobank
por: North, Teri-Louise, et al.
Publicado: (2023)

Evidence That Emmetropization Buffers Against Both Genetic and Environmental Risk Factors for Myopia
por: Pozarickij, Alfred, et al.
Publicado: (2020)

Evaluation of the causal effects between subjective wellbeing and cardiometabolic health: mendelian randomisation study
por: Lawn, Rebecca B, et al.
Publicado: (2018)

Quantile regression analysis reveals widespread evidence for gene-environment or gene-gene interactions in myopia development
por: Pozarickij, Alfred, et al.
Publicado: (2019)

Geographical Variation in Likely Myopia and Environmental Risk Factors: A Multilevel Cross Classified Analysis of A UK Cohort
por: Morris, Tim T, et al.
Publicado: (2019)

Mendelian randomization study confirms causal relationship between myopia and vitreous disorders
por: Xu, Jiayu, et al.
Publicado: (2023)

Education interacts with genetic variants near GJD2, RBFOX1, LAMA2, KCNQ5 and LRRC4C to confer susceptibility to myopia
por: Clark, Rosie, et al.
Publicado: (2022)

Genetic Variants Associated With Human Eye Size Are Distinct From Those Conferring Susceptibility to Myopia
por: Plotnikov, Denis, et al.
Publicado: (2021)

Mendelian Randomisation and Causal Inference in Observational Epidemiology
por: Sheehan, Nuala A, et al.
Publicado: (2008)

Mendel’s laws, Mendelian randomization and causal inference in observational data: substantive and nomenclatural issues
por: Davey Smith, George, et al.
Publicado: (2020)

A Genome-Wide Association Study for Susceptibility to Visual Experience-Induced Myopia
por: Huang, Yu, et al.
Publicado: (2019)

Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians
por: Davies, Neil M, et al.
Publicado: (2018)

Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study
por: Carter, Alice R, et al.
Publicado: (2019)

Joubert Syndrome Presenting with Motor Delay and Oculomotor Apraxia
por: Gill, Harjinder, et al.
Publicado: (2011)

Grandmothers’ smoking in pregnancy is associated with a reduced prevalence of early-onset myopia
por: Williams, Cathy, et al.
Publicado: (2019)

Axial length growth and the risk of developing myopia in European children
por: Tideman, Jan Willem Lodewijk, et al.
Publicado: (2017)

Childhood febrile illness and the risk of myopia in UK Biobank participants
por: Guggenheim, J A, et al.
Publicado: (2016)

Editorial: Exploiting genetics and genomics to improve the understanding of eye diseases
por: Plotnikov, Denis, et al.
Publicado: (2023)

Author Correction: Grandmothers’ smoking in pregnancy is associated with a reduced prevalence of early-onset myopia
por: Williams, Cathy, et al.
Publicado: (2019)

Education and coronary heart disease: mendelian randomisation study
por: Tillmann, Taavi, et al.
Publicado: (2017)

Mendelian randomization: genetic anchors for causal inference in epidemiological studies
por: Davey Smith, George, et al.
Publicado: (2014)

Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study
por: Noyce, Alastair J., et al.
Publicado: (2017)

Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study
por: Wootton, Robyn E., et al.
Publicado: (2020)

Examining the possible causal relationship between lung function, COPD and Alzheimer’s disease: a Mendelian randomisation study
por: Higbee, Daniel, et al.
Publicado: (2021)

Mendelian randomisation analysis of the effect of educational attainment and cognitive ability on smoking behaviour
por: Sanderson, Eleanor, et al.
Publicado: (2019)

Searching for the causal effects of body mass index in over 300 000 participants in UK Biobank, using Mendelian randomization
por: Millard, Louise A. C., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_866gori3hi485epnopdmn2bqa4