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The AKAP Cypher/Zasp contributes to β-adrenergic/PKA stimulation of cardiac Ca(V)1.2 calcium channels

Stimulation of the L-type Ca(2+) current conducted by Ca(V)1.2 channels in cardiac myocytes by the β-adrenergic/protein kinase A (PKA) signaling pathway requires anchoring of PKA to the Ca(V)1.2 channel by an A-kinase anchoring protein (AKAP). However, the AKAP(s) responsible for regulation in vivo...

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Detalles Bibliográficos
Autores principales: Yu, Haijie, Yuan, Can, Westenbroek, Ruth E., Catterall, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987873/
https://www.ncbi.nlm.nih.gov/pubmed/29743299
http://dx.doi.org/10.1085/jgp.201711818

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