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Histidine(168) is crucial for ΔpH-dependent gating of the human voltage-gated proton channel, hH(V)1

We recently identified a voltage-gated proton channel gene in the snail Helisoma trivolvis, HtH(V)1, and determined its electrophysiological properties. Consistent with early studies of proton currents in snail neurons, HtH(V)1 opens rapidly, but it unexpectedly exhibits uniquely defective sensitivi...

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Detalles Bibliográficos
Autores principales: Cherny, Vladimir V., Morgan, Deri, Thomas, Sarah, Smith, Susan M.E., DeCoursey, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987877/
https://www.ncbi.nlm.nih.gov/pubmed/29743300
http://dx.doi.org/10.1085/jgp.201711968