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Histidine(168) is crucial for ΔpH-dependent gating of the human voltage-gated proton channel, hH(V)1
We recently identified a voltage-gated proton channel gene in the snail Helisoma trivolvis, HtH(V)1, and determined its electrophysiological properties. Consistent with early studies of proton currents in snail neurons, HtH(V)1 opens rapidly, but it unexpectedly exhibits uniquely defective sensitivi...
Autores principales: | Cherny, Vladimir V., Morgan, Deri, Thomas, Sarah, Smith, Susan M.E., DeCoursey, Thomas E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987877/ https://www.ncbi.nlm.nih.gov/pubmed/29743300 http://dx.doi.org/10.1085/jgp.201711968 |
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