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Upper-Extremity Deep Vein Thrombosis in Patients With Breast Cancer With Chest Versus Arm Central Venous Port Catheters

Most of the patients undergoing treatment for cancer require placement of a totally implantable venous access device to facilitate safe delivery of chemotherapy. However, implantable ports also increase the risk of deep vein thrombosis and related complications in this high-risk population. The obje...

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Autores principales: Tippit, Danielle, Siegel, Eric, Ochoa, Daniella, Pennisi, Angela, Hill, Erica, Merrill, Amelia, Rowe, Mark, Henry-Tillman, Ronda, Ananthula, Aneesha, Makhoul, Issam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987887/
https://www.ncbi.nlm.nih.gov/pubmed/29881287
http://dx.doi.org/10.1177/1178223418771909
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author Tippit, Danielle
Siegel, Eric
Ochoa, Daniella
Pennisi, Angela
Hill, Erica
Merrill, Amelia
Rowe, Mark
Henry-Tillman, Ronda
Ananthula, Aneesha
Makhoul, Issam
author_facet Tippit, Danielle
Siegel, Eric
Ochoa, Daniella
Pennisi, Angela
Hill, Erica
Merrill, Amelia
Rowe, Mark
Henry-Tillman, Ronda
Ananthula, Aneesha
Makhoul, Issam
author_sort Tippit, Danielle
collection PubMed
description Most of the patients undergoing treatment for cancer require placement of a totally implantable venous access device to facilitate safe delivery of chemotherapy. However, implantable ports also increase the risk of deep vein thrombosis and related complications in this high-risk population. The objective of this study was to assess the incidence of upper-extremity deep vein thrombosis (UEDVT) in patients with breast cancer to determine whether the risk of UEDVT was higher with chest versus arm ports, as well as to determine the importance of previously reported risk factors predisposing to UEDVT in the setting of active cancer. We retrospectively reviewed the medical records of 297 women with breast cancer who had ports placed in our institution between the dates of December 1, 2010, and December 31, 2016. The primary outcome was the development of radiologically confirmed UEDVT ipsilateral to the implanted port. Overall, 17 of 297 study subjects (5.7%) were found to have UEDVT. There was 1 documented case of associated pulmonary embolism. Fourteen (9.5%) of 147 subjects with arm ports experienced UEDVT compared with only 3 (2.0%) of 150 subjects with chest ports (P = .0056). Thus, implantation of arm ports as opposed to chest ports may be associated with a higher rate of UEDVT in patients with breast cancer.
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spelling pubmed-59878872018-06-07 Upper-Extremity Deep Vein Thrombosis in Patients With Breast Cancer With Chest Versus Arm Central Venous Port Catheters Tippit, Danielle Siegel, Eric Ochoa, Daniella Pennisi, Angela Hill, Erica Merrill, Amelia Rowe, Mark Henry-Tillman, Ronda Ananthula, Aneesha Makhoul, Issam Breast Cancer (Auckl) Original Research Most of the patients undergoing treatment for cancer require placement of a totally implantable venous access device to facilitate safe delivery of chemotherapy. However, implantable ports also increase the risk of deep vein thrombosis and related complications in this high-risk population. The objective of this study was to assess the incidence of upper-extremity deep vein thrombosis (UEDVT) in patients with breast cancer to determine whether the risk of UEDVT was higher with chest versus arm ports, as well as to determine the importance of previously reported risk factors predisposing to UEDVT in the setting of active cancer. We retrospectively reviewed the medical records of 297 women with breast cancer who had ports placed in our institution between the dates of December 1, 2010, and December 31, 2016. The primary outcome was the development of radiologically confirmed UEDVT ipsilateral to the implanted port. Overall, 17 of 297 study subjects (5.7%) were found to have UEDVT. There was 1 documented case of associated pulmonary embolism. Fourteen (9.5%) of 147 subjects with arm ports experienced UEDVT compared with only 3 (2.0%) of 150 subjects with chest ports (P = .0056). Thus, implantation of arm ports as opposed to chest ports may be associated with a higher rate of UEDVT in patients with breast cancer. SAGE Publications 2018-04-20 /pmc/articles/PMC5987887/ /pubmed/29881287 http://dx.doi.org/10.1177/1178223418771909 Text en © The Author(s) 2018 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research
Tippit, Danielle
Siegel, Eric
Ochoa, Daniella
Pennisi, Angela
Hill, Erica
Merrill, Amelia
Rowe, Mark
Henry-Tillman, Ronda
Ananthula, Aneesha
Makhoul, Issam
Upper-Extremity Deep Vein Thrombosis in Patients With Breast Cancer With Chest Versus Arm Central Venous Port Catheters
title Upper-Extremity Deep Vein Thrombosis in Patients With Breast Cancer With Chest Versus Arm Central Venous Port Catheters
title_full Upper-Extremity Deep Vein Thrombosis in Patients With Breast Cancer With Chest Versus Arm Central Venous Port Catheters
title_fullStr Upper-Extremity Deep Vein Thrombosis in Patients With Breast Cancer With Chest Versus Arm Central Venous Port Catheters
title_full_unstemmed Upper-Extremity Deep Vein Thrombosis in Patients With Breast Cancer With Chest Versus Arm Central Venous Port Catheters
title_short Upper-Extremity Deep Vein Thrombosis in Patients With Breast Cancer With Chest Versus Arm Central Venous Port Catheters
title_sort upper-extremity deep vein thrombosis in patients with breast cancer with chest versus arm central venous port catheters
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987887/
https://www.ncbi.nlm.nih.gov/pubmed/29881287
http://dx.doi.org/10.1177/1178223418771909
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