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Spatial distribution and function of T follicular regulatory cells in human lymph nodes
T follicular regulatory (Tfr) cells are a population of CD4(+) T cells that express regulatory T cell markers and have been shown to suppress humoral immunity. However, the precise mechanisms and location of Tfr-mediated suppression in the lymph node (LN) microenvironment are unknown. Using highly m...
Autores principales: | Sayin, Ismail, Radtke, Andrea J., Vella, Laura A., Jin, Wenjie, Wherry, E. John, Buggert, Marcus, Betts, Michael R., Herati, Ramin S., Germain, Ronald N., Canaday, David H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987920/ https://www.ncbi.nlm.nih.gov/pubmed/29769249 http://dx.doi.org/10.1084/jem.20171940 |
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