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Inhibition of UGT8 suppresses basal-like breast cancer progression by attenuating sulfatide–αVβ5 axis
Basal-like breast cancer (BLBC) is associated with a poor clinical outcome as a result of the few treatment options and poor therapeutic response. Here, we report that elevated expression of urine diphosphate–galactose ceramide galactosyltransferase (UGT8) specifically occurs in BLBC and predicts po...
Autores principales: | Cao, Qianhua, Chen, Xingyu, Wu, Xuebiao, Liao, Ruocen, Huang, Panpan, Tan, Yanjia, Wang, Li, Ren, Guoping, Huang, Jian, Dong, Chenfang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987921/ https://www.ncbi.nlm.nih.gov/pubmed/29728441 http://dx.doi.org/10.1084/jem.20172048 |
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