Cargando…

Tissue-resident macrophages in the intestine are long lived and defined by Tim-4 and CD4 expression

A defining feature of resident gut macrophages is their high replenishment rate from blood monocytes attributed to tonic commensal stimulation of this site. In contrast, almost all other tissues contain locally maintained macrophage populations, which coexist with monocyte-replenished cells at homeo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shaw, Tovah N., Houston, Stephanie A., Wemyss, Kelly, Bridgeman, Hayley M., Barbera, Thomas A., Zangerle-Murray, Tamsin, Strangward, Patrick, Ridley, Amanda J.L., Wang, Ping, Tamoutounour, Samira, Allen, Judith E., Konkel, Joanne E., Grainger, John R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987925/ https://www.ncbi.nlm.nih.gov/pubmed/29789388 http://dx.doi.org/10.1084/jem.20180019

Ejemplares similares

Macrophages in gastrointestinal homeostasis and inflammation
por: Grainger, John R., et al.
Publicado: (2017)

Hematopoietic stem and progenitor cells are present in healthy gingiva tissue
por: Krishnan, Siddharth, et al.
Publicado: (2021)

Amphiregulin-producing γδ T cells are vital for safeguarding oral barrier immune homeostasis
por: Krishnan, Siddharth, et al.
Publicado: (2018)

Long-Lived CD4(+)IFN-γ(+) T Cells rather than Short-Lived CD4(+)IFN-γ(+)IL-10(+) T Cells Initiate Rapid IL-10 Production To Suppress Anamnestic T Cell Responses during Secondary Malaria Infection
por: Villegas-Mendez, Ana, et al.
Publicado: (2016)

Mertk Interacts with Tim-4 to Enhance Tim-4-Mediated Efferocytosis
por: Moon, Byeongjin, et al.
Publicado: (2020)

Parasite-Specific CD4(+) IFN-γ(+) IL-10(+) T Cells Distribute within Both Lymphoid and Nonlymphoid Compartments and Are Controlled Systemically by Interleukin-27 and ICOS during Blood-Stage Malaria Infection
por: Villegas-Mendez, Ana, et al.
Publicado: (2015)

On-going Mechanical Damage from Mastication Drives Homeostatic Th17 Cell Responses at the Oral Barrier
por: Dutzan, Nicolas, et al.
Publicado: (2017)

Mast cell activation is enhanced by Tim1:Tim4 interaction but not by Tim-1 antibodies
por: Phong, Binh, et al.
Publicado: (2016)

Single-Cell Profiling Defines Transcriptomic Signatures Specific to Tumor-Reactive versus Virus-Responsive CD4(+) T Cells
por: Magen, Assaf, et al.
Publicado: (2019)

Tim-4 Inhibits NO Generation by Murine Macrophages
por: Xu, Li-yun, et al.
Publicado: (2015)

Tim-4 in Health and Disease: Friend or Foe?
por: Liu, Wen, et al.
Publicado: (2020)

Tim-3 Expression Defines Regulatory T Cells in Human Tumors
por: Yan, Jing, et al.
Publicado: (2013)

Gamma Interferon Mediates Experimental Cerebral Malaria by Signaling within Both the Hematopoietic and Nonhematopoietic Compartments
por: Villegas-Mendez, Ana, et al.
Publicado: (2017)

Role of TIM-4 in innate or adaptive immune response
por: Nurtanio, Natasha, et al.
Publicado: (2011)

EphA2 Interacts with Tim-4 through Association between Its FN3 Domain and the IgV Domain of Tim-4
por: Moon, Byeongjin, et al.
Publicado: (2021)

Association of Tim-3/Gal-9 Axis with NLRC4 Inflammasome in Glioma Malignancy: Tim-3/Gal-9 Induce the NLRC4 Inflammasome
por: Sim, JeongMin, et al.
Publicado: (2022)

TIM4-TIM1 interaction modulates Th2 pattern inflammation through enhancing SIRT1 expression
por: Hu, Tianyong, et al.
Publicado: (2017)

Function and characteristics of TIM-4 in immune regulation and disease (Review)
por: Wang, Ziyao, et al.
Publicado: (2022)

Systemic instruction of cell-mediated immunity by the intestinal microbiome
por: Grainger, John, et al.
Publicado: (2018)

Tim1 and Tim3 are not essential for experimental allergic asthma
por: Barlow, J L, et al.
Publicado: (2011)

Alterations in T and B cell function persist in convalescent COVID-19 patients
por: Shuwa, Halima A., et al.
Publicado: (2021)

The Helminth Parasite Heligmosomoides polygyrus Attenuates EAE in an IL-4Rα-Dependent Manner
por: White, Madeleine P. J., et al.
Publicado: (2020)

The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis
por: Flannagan, Ronald S., et al.
Publicado: (2014)

TIM-4 is expressed on invariant NKT cells but dispensable for their development and function
por: Zhang, Xilin, et al.
Publicado: (2016)

Tim-4 functions as a scavenger receptor for phagocytosis of exogenous particles
por: Min, Chanhyuk, et al.
Publicado: (2020)

Inhibition of TIM‐4 protects against cerebral ischaemia‐reperfusion injury
por: Zheng, Lifang, et al.
Publicado: (2019)

NOX4–TIM23 interaction regulates NOX4 mitochondrial import and metabolic reprogramming
por: Pandey, Jyotsana, et al.
Publicado: (2023)

Histone acetyltransferease p300 modulates TIM4 expression in dendritic cells
por: Yang, Bo, et al.
Publicado: (2016)

N-Glycosylation at Asn291 Stabilizes TIM-4 and Promotes the Metastasis of NSCLC
por: Chen, Siyuan, et al.
Publicado: (2022)

Tim Burton /
por: Marcos Arza, Marcos
Publicado: (2007)

Tim Lou
por: Lou, Hou Keong
Publicado: (2009)

Defining the Substrate Spectrum of the TIM22 Complex Identifies Pyruvate Carrier Subunits as Unconventional Cargos
por: Gomkale, Ridhima, et al.
Publicado: (2020)

Memory CD8(+) T cells exhibit tissue imprinting and non‐stable exposure‐dependent reactivation characteristics following blood‐stage Plasmodium berghei ANKA infections
por: Shaw, Tovah N., et al.
Publicado: (2021)

TIM-Finder: A new method for identifying TIM-barrel proteins
por: Si, Jing-Na, et al.
Publicado: (2009)

Expression of Tim4 in Glioma and its Regulatory Role in LN-18 Glioma Cells
por: Li, Weiguo, et al.
Publicado: (2016)

Hepatic Ischemic Preconditioning Alleviates Ischemia-Reperfusion Injury by Decreasing TIM4 Expression
por: Zhang, Yu, et al.
Publicado: (2018)

Role of TIM-4 in exosome-dependent entry of HIV-1 into human immune cells
por: Sims, Brian, et al.
Publicado: (2017)

Infection-Induced Resistance to Experimental Cerebral Malaria Is Dependent Upon Secreted Antibody-Mediated Inhibition of Pathogenic CD8(+) T Cell Responses
por: Shaw, Tovah N., et al.
Publicado: (2019)

Altered expression of Tim family molecules and an imbalanced ratio of Tim-3 to Tim-1 expression in patients with type 1 diabetes
por: Liu, Yikai, et al.
Publicado: (2022)

The Tim54p–Tim22p Complex Mediates Insertion of Proteins into the Mitochondrial Inner Membrane
por: Kerscher, Oliver, et al.
Publicado: (1997)

Cannot write session to /tmp/vufind_sessions/sess_uh4re9stgto0bpre4rttf5bp3g