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Decomposing the Apoptosis Pathway Into Biologically Interpretable Principal Components

Principal component analysis (PCA) is one of the most common techniques in the analysis of biological data sets, but applying PCA raises 2 challenges. First, one must determine the number of significant principal components (PCs). Second, because each PC is a linear combination of genes, it rarely h...

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Detalles Bibliográficos
Autores principales: Wang, Min, Kornblau, Steven M, Coombes, Kevin R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987987/
https://www.ncbi.nlm.nih.gov/pubmed/29881252
http://dx.doi.org/10.1177/1176935118771082