Cerebrospinal fluid mtDNA concentration is elevated in multiple sclerosis disease and responds to treatment

BACKGROUND: Mitochondrial dysfunction is increasingly recognized as an important feature of multiple sclerosis (MS) pathology and may be relevant for clinical disease progression. However, it is unknown whether mitochondrial DNA (mtDNA) levels in the cerebrospinal fluid (CSF) associate with disease...

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Detalles Bibliográficos
Autores principales: Leurs, Cyra E, Podlesniy, Petar, Trullas, Ramon, Balk, Lisanne, Steenwijk, Martijn D, Malekzadeh, Arjan, Piehl, Fredrik, Uitdehaag, Bernard MJ, Killestein, Joep, van Horssen, Jack, Teunissen, CE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Original Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987988/
https://www.ncbi.nlm.nih.gov/pubmed/28294696
http://dx.doi.org/10.1177/1352458517699874

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