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Adult ADHD and Comorbid Somatic Disease: A Systematic Literature Review
Objective: To systematically review, synthesize, and appraise available evidence, connecting adult ADHD with somatic disease. Method: Embase, Psychinfo, and Medline databases were searched for studies published from 1994 to 2015 addressing adult ADHD and somatic comorbidity. Somatic conditions were...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987989/ https://www.ncbi.nlm.nih.gov/pubmed/27664125 http://dx.doi.org/10.1177/1087054716669589 |
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author | Instanes, Johanne Telnes Klungsøyr, Kari Halmøy, Anne Fasmer, Ole Bernt Haavik, Jan |
author_facet | Instanes, Johanne Telnes Klungsøyr, Kari Halmøy, Anne Fasmer, Ole Bernt Haavik, Jan |
author_sort | Instanes, Johanne Telnes |
collection | PubMed |
description | Objective: To systematically review, synthesize, and appraise available evidence, connecting adult ADHD with somatic disease. Method: Embase, Psychinfo, and Medline databases were searched for studies published from 1994 to 2015 addressing adult ADHD and somatic comorbidity. Somatic conditions were classified according to International Classification of Diseases (ICD-10) codes. Levels of evidence were graded as inconclusive, tentative, or well documented. Results: Most of the 126 studies included in the qualitative synthesis were small and of modest quality. Obesity, sleep disorders, and asthma were well-documented comorbidities in adult ADHD. Tentative evidence was found for an association between adult ADHD and migraine and celiac disease. In a large health registry study, cardiovascular disease was not associated with adult ADHD. Conclusion: There are few large systematic studies using standardized diagnostic criteria evaluating adult ADHD and somatic comorbidities. Significant associations are found between adult ADHD and several somatic diseases, and these are important to consider when assessing and treating either adult ADHD or the somatic diseases. |
format | Online Article Text |
id | pubmed-5987989 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-59879892018-06-11 Adult ADHD and Comorbid Somatic Disease: A Systematic Literature Review Instanes, Johanne Telnes Klungsøyr, Kari Halmøy, Anne Fasmer, Ole Bernt Haavik, Jan J Atten Disord Current Perspectives Objective: To systematically review, synthesize, and appraise available evidence, connecting adult ADHD with somatic disease. Method: Embase, Psychinfo, and Medline databases were searched for studies published from 1994 to 2015 addressing adult ADHD and somatic comorbidity. Somatic conditions were classified according to International Classification of Diseases (ICD-10) codes. Levels of evidence were graded as inconclusive, tentative, or well documented. Results: Most of the 126 studies included in the qualitative synthesis were small and of modest quality. Obesity, sleep disorders, and asthma were well-documented comorbidities in adult ADHD. Tentative evidence was found for an association between adult ADHD and migraine and celiac disease. In a large health registry study, cardiovascular disease was not associated with adult ADHD. Conclusion: There are few large systematic studies using standardized diagnostic criteria evaluating adult ADHD and somatic comorbidities. Significant associations are found between adult ADHD and several somatic diseases, and these are important to consider when assessing and treating either adult ADHD or the somatic diseases. SAGE Publications 2016-09-01 2018-02 /pmc/articles/PMC5987989/ /pubmed/27664125 http://dx.doi.org/10.1177/1087054716669589 Text en © The Author(s) 2016 http://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution 4.0 License (http://www.creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Current Perspectives Instanes, Johanne Telnes Klungsøyr, Kari Halmøy, Anne Fasmer, Ole Bernt Haavik, Jan Adult ADHD and Comorbid Somatic Disease: A Systematic Literature Review |
title | Adult ADHD and Comorbid Somatic Disease: A Systematic Literature Review |
title_full | Adult ADHD and Comorbid Somatic Disease: A Systematic Literature Review |
title_fullStr | Adult ADHD and Comorbid Somatic Disease: A Systematic Literature Review |
title_full_unstemmed | Adult ADHD and Comorbid Somatic Disease: A Systematic Literature Review |
title_short | Adult ADHD and Comorbid Somatic Disease: A Systematic Literature Review |
title_sort | adult adhd and comorbid somatic disease: a systematic literature review |
topic | Current Perspectives |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987989/ https://www.ncbi.nlm.nih.gov/pubmed/27664125 http://dx.doi.org/10.1177/1087054716669589 |
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