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Adult ADHD and Comorbid Somatic Disease: A Systematic Literature Review

Objective: To systematically review, synthesize, and appraise available evidence, connecting adult ADHD with somatic disease. Method: Embase, Psychinfo, and Medline databases were searched for studies published from 1994 to 2015 addressing adult ADHD and somatic comorbidity. Somatic conditions were...

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Autores principales: Instanes, Johanne Telnes, Klungsøyr, Kari, Halmøy, Anne, Fasmer, Ole Bernt, Haavik, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987989/
https://www.ncbi.nlm.nih.gov/pubmed/27664125
http://dx.doi.org/10.1177/1087054716669589
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author Instanes, Johanne Telnes
Klungsøyr, Kari
Halmøy, Anne
Fasmer, Ole Bernt
Haavik, Jan
author_facet Instanes, Johanne Telnes
Klungsøyr, Kari
Halmøy, Anne
Fasmer, Ole Bernt
Haavik, Jan
author_sort Instanes, Johanne Telnes
collection PubMed
description Objective: To systematically review, synthesize, and appraise available evidence, connecting adult ADHD with somatic disease. Method: Embase, Psychinfo, and Medline databases were searched for studies published from 1994 to 2015 addressing adult ADHD and somatic comorbidity. Somatic conditions were classified according to International Classification of Diseases (ICD-10) codes. Levels of evidence were graded as inconclusive, tentative, or well documented. Results: Most of the 126 studies included in the qualitative synthesis were small and of modest quality. Obesity, sleep disorders, and asthma were well-documented comorbidities in adult ADHD. Tentative evidence was found for an association between adult ADHD and migraine and celiac disease. In a large health registry study, cardiovascular disease was not associated with adult ADHD. Conclusion: There are few large systematic studies using standardized diagnostic criteria evaluating adult ADHD and somatic comorbidities. Significant associations are found between adult ADHD and several somatic diseases, and these are important to consider when assessing and treating either adult ADHD or the somatic diseases.
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spelling pubmed-59879892018-06-11 Adult ADHD and Comorbid Somatic Disease: A Systematic Literature Review Instanes, Johanne Telnes Klungsøyr, Kari Halmøy, Anne Fasmer, Ole Bernt Haavik, Jan J Atten Disord Current Perspectives Objective: To systematically review, synthesize, and appraise available evidence, connecting adult ADHD with somatic disease. Method: Embase, Psychinfo, and Medline databases were searched for studies published from 1994 to 2015 addressing adult ADHD and somatic comorbidity. Somatic conditions were classified according to International Classification of Diseases (ICD-10) codes. Levels of evidence were graded as inconclusive, tentative, or well documented. Results: Most of the 126 studies included in the qualitative synthesis were small and of modest quality. Obesity, sleep disorders, and asthma were well-documented comorbidities in adult ADHD. Tentative evidence was found for an association between adult ADHD and migraine and celiac disease. In a large health registry study, cardiovascular disease was not associated with adult ADHD. Conclusion: There are few large systematic studies using standardized diagnostic criteria evaluating adult ADHD and somatic comorbidities. Significant associations are found between adult ADHD and several somatic diseases, and these are important to consider when assessing and treating either adult ADHD or the somatic diseases. SAGE Publications 2016-09-01 2018-02 /pmc/articles/PMC5987989/ /pubmed/27664125 http://dx.doi.org/10.1177/1087054716669589 Text en © The Author(s) 2016 http://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution 4.0 License (http://www.creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Current Perspectives
Instanes, Johanne Telnes
Klungsøyr, Kari
Halmøy, Anne
Fasmer, Ole Bernt
Haavik, Jan
Adult ADHD and Comorbid Somatic Disease: A Systematic Literature Review
title Adult ADHD and Comorbid Somatic Disease: A Systematic Literature Review
title_full Adult ADHD and Comorbid Somatic Disease: A Systematic Literature Review
title_fullStr Adult ADHD and Comorbid Somatic Disease: A Systematic Literature Review
title_full_unstemmed Adult ADHD and Comorbid Somatic Disease: A Systematic Literature Review
title_short Adult ADHD and Comorbid Somatic Disease: A Systematic Literature Review
title_sort adult adhd and comorbid somatic disease: a systematic literature review
topic Current Perspectives
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987989/
https://www.ncbi.nlm.nih.gov/pubmed/27664125
http://dx.doi.org/10.1177/1087054716669589
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