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Cardiac complications after stroke: protocol for a systematic review and meta-analysis

INTRODUCTION: Stroke is the second most common cause of death after ischaemic heart diseases and the third leading cause of disability worldwide. The contribution of cardiac complications to the mortality of patients with stroke is variable across studies, ranging from 12.5% to 22.7%. Many of these...

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Autores principales: Kenmogne-Domning, Guidelle Héloïse, Kamtchum-Tatuene, Joseph, Noumegni, Steve Raoul, Fokoua-Dongmo, Christophe Maxime, Zafack, Joseline Guetsop, Noubiap, Jean Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988104/
https://www.ncbi.nlm.nih.gov/pubmed/29794102
http://dx.doi.org/10.1136/bmjopen-2017-021416
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author Kenmogne-Domning, Guidelle Héloïse
Kamtchum-Tatuene, Joseph
Noumegni, Steve Raoul
Fokoua-Dongmo, Christophe Maxime
Zafack, Joseline Guetsop
Noubiap, Jean Jacques
author_facet Kenmogne-Domning, Guidelle Héloïse
Kamtchum-Tatuene, Joseph
Noumegni, Steve Raoul
Fokoua-Dongmo, Christophe Maxime
Zafack, Joseline Guetsop
Noubiap, Jean Jacques
author_sort Kenmogne-Domning, Guidelle Héloïse
collection PubMed
description INTRODUCTION: Stroke is the second most common cause of death after ischaemic heart diseases and the third leading cause of disability worldwide. The contribution of cardiac complications to the mortality of patients with stroke is variable across studies, ranging from 12.5% to 22.7%. Many of these cardiac complications are preventable, and early recognition and adequate management guided by appropriate up-to-date knowledge of their relative incidence and fatality can help to improve patients’ outcomes. This systematic review aims to summarise the available data on the burden of cardiac complications after stroke. METHODS AND ANALYSIS: This review will include all cross-sectional, case–control and cohort studies and clinical trials published between 1 January 1950 and 31 December 2017, involving adults and/or children, and reporting on the prevalence, the incidence and/or the mortality of cardiac complications after stroke. Two reviewers will independently screen titles and abstracts of records retrieved from PubMed, Excerpta Medica Database, ISI Web of Science and the Cumulative Index to Nursing and Allied Health Literature for eligibility, and then assess the risk of bias and quality of reporting to select the studies which will be included. All authors will contribute to the retrieval of full texts of eligible records and data extraction. Heterogeneity across studies will be evaluated by the χ(2) test on Cochran’s Q statistic. Study-specific estimates of the prevalence, incidence and mortality of cardiac complications after stroke across studies will be pooled through random-effect or fixed-effect meta-analysis depending on the source of the heterogeneity, after stabilising the variance of individual studies using the Freeman-Tukey double arcsine transformation. Visual analysis of funnel plots and Egger’s test will be done to detect small-study effect. ETHICS AND DISSEMINATION: This review and meta-analysis will be based on published data and will therefore not require a specific ethical clearance. The results will be published in peer-reviewed journals. PROSPERO REGISTRATION NUMBER: CRD42018082551.
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spelling pubmed-59881042018-06-07 Cardiac complications after stroke: protocol for a systematic review and meta-analysis Kenmogne-Domning, Guidelle Héloïse Kamtchum-Tatuene, Joseph Noumegni, Steve Raoul Fokoua-Dongmo, Christophe Maxime Zafack, Joseline Guetsop Noubiap, Jean Jacques BMJ Open Neurology INTRODUCTION: Stroke is the second most common cause of death after ischaemic heart diseases and the third leading cause of disability worldwide. The contribution of cardiac complications to the mortality of patients with stroke is variable across studies, ranging from 12.5% to 22.7%. Many of these cardiac complications are preventable, and early recognition and adequate management guided by appropriate up-to-date knowledge of their relative incidence and fatality can help to improve patients’ outcomes. This systematic review aims to summarise the available data on the burden of cardiac complications after stroke. METHODS AND ANALYSIS: This review will include all cross-sectional, case–control and cohort studies and clinical trials published between 1 January 1950 and 31 December 2017, involving adults and/or children, and reporting on the prevalence, the incidence and/or the mortality of cardiac complications after stroke. Two reviewers will independently screen titles and abstracts of records retrieved from PubMed, Excerpta Medica Database, ISI Web of Science and the Cumulative Index to Nursing and Allied Health Literature for eligibility, and then assess the risk of bias and quality of reporting to select the studies which will be included. All authors will contribute to the retrieval of full texts of eligible records and data extraction. Heterogeneity across studies will be evaluated by the χ(2) test on Cochran’s Q statistic. Study-specific estimates of the prevalence, incidence and mortality of cardiac complications after stroke across studies will be pooled through random-effect or fixed-effect meta-analysis depending on the source of the heterogeneity, after stabilising the variance of individual studies using the Freeman-Tukey double arcsine transformation. Visual analysis of funnel plots and Egger’s test will be done to detect small-study effect. ETHICS AND DISSEMINATION: This review and meta-analysis will be based on published data and will therefore not require a specific ethical clearance. The results will be published in peer-reviewed journals. PROSPERO REGISTRATION NUMBER: CRD42018082551. BMJ Publishing Group 2018-05-24 /pmc/articles/PMC5988104/ /pubmed/29794102 http://dx.doi.org/10.1136/bmjopen-2017-021416 Text en © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Neurology
Kenmogne-Domning, Guidelle Héloïse
Kamtchum-Tatuene, Joseph
Noumegni, Steve Raoul
Fokoua-Dongmo, Christophe Maxime
Zafack, Joseline Guetsop
Noubiap, Jean Jacques
Cardiac complications after stroke: protocol for a systematic review and meta-analysis
title Cardiac complications after stroke: protocol for a systematic review and meta-analysis
title_full Cardiac complications after stroke: protocol for a systematic review and meta-analysis
title_fullStr Cardiac complications after stroke: protocol for a systematic review and meta-analysis
title_full_unstemmed Cardiac complications after stroke: protocol for a systematic review and meta-analysis
title_short Cardiac complications after stroke: protocol for a systematic review and meta-analysis
title_sort cardiac complications after stroke: protocol for a systematic review and meta-analysis
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988104/
https://www.ncbi.nlm.nih.gov/pubmed/29794102
http://dx.doi.org/10.1136/bmjopen-2017-021416
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