Evaluation of Online Plan Adaptation Strategies for the 1.5T MR-linac Based on “First-In-Man” Treatments

The superior soft tissue contrast provided by magnetic resonance (MR) images on the 1.5T MR-linac allows for the incorporation of patient anatomy information. In this retrospective case study, we present the simulated dosimetric effects and timings of full online replanning as compared to the five p...

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Autores principales: Winkel, Dennis, Bol, Gijsbert H, Kiekebosch, Ilse H, Van Asselen, Bram, Kroon, Petra S, Jürgenliemk-Schulz, Ina M, Raaymakers, Bas W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Medical Physics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988167/
https://www.ncbi.nlm.nih.gov/pubmed/29876153
http://dx.doi.org/10.7759/cureus.2431
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author Winkel, Dennis
Bol, Gijsbert H
Kiekebosch, Ilse H
Van Asselen, Bram
Kroon, Petra S
Jürgenliemk-Schulz, Ina M
Raaymakers, Bas W
author_facet Winkel, Dennis
Bol, Gijsbert H
Kiekebosch, Ilse H
Van Asselen, Bram
Kroon, Petra S
Jürgenliemk-Schulz, Ina M
Raaymakers, Bas W
author_sort Winkel, Dennis
collection PubMed
description The superior soft tissue contrast provided by magnetic resonance (MR) images on the 1.5T MR-linac allows for the incorporation of patient anatomy information. In this retrospective case study, we present the simulated dosimetric effects and timings of full online replanning as compared to the five plan adaptation methods currently available on the 1.5T MR-linac treatment system. For this case, it is possible to create treatment plans with all six methods within a time slot suitable for an online treatment procedure. However, large dosimetric differences between the plan adaptation methods and full online replanning are present with regards to target coverage and dose to organs at risk (OARs).
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spelling pubmed-59881672018-06-06 Evaluation of Online Plan Adaptation Strategies for the 1.5T MR-linac Based on “First-In-Man” Treatments Winkel, Dennis Bol, Gijsbert H Kiekebosch, Ilse H Van Asselen, Bram Kroon, Petra S Jürgenliemk-Schulz, Ina M Raaymakers, Bas W Cureus Medical Physics The superior soft tissue contrast provided by magnetic resonance (MR) images on the 1.5T MR-linac allows for the incorporation of patient anatomy information. In this retrospective case study, we present the simulated dosimetric effects and timings of full online replanning as compared to the five plan adaptation methods currently available on the 1.5T MR-linac treatment system. For this case, it is possible to create treatment plans with all six methods within a time slot suitable for an online treatment procedure. However, large dosimetric differences between the plan adaptation methods and full online replanning are present with regards to target coverage and dose to organs at risk (OARs). Cureus 2018-04-05 /pmc/articles/PMC5988167/ /pubmed/29876153 http://dx.doi.org/10.7759/cureus.2431 Text en Copyright © 2018, Winkel et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Medical Physics
Winkel, Dennis
Bol, Gijsbert H
Kiekebosch, Ilse H
Van Asselen, Bram
Kroon, Petra S
Jürgenliemk-Schulz, Ina M
Raaymakers, Bas W
Evaluation of Online Plan Adaptation Strategies for the 1.5T MR-linac Based on “First-In-Man” Treatments
title Evaluation of Online Plan Adaptation Strategies for the 1.5T MR-linac Based on “First-In-Man” Treatments
title_full Evaluation of Online Plan Adaptation Strategies for the 1.5T MR-linac Based on “First-In-Man” Treatments
title_fullStr Evaluation of Online Plan Adaptation Strategies for the 1.5T MR-linac Based on “First-In-Man” Treatments
title_full_unstemmed Evaluation of Online Plan Adaptation Strategies for the 1.5T MR-linac Based on “First-In-Man” Treatments
title_short Evaluation of Online Plan Adaptation Strategies for the 1.5T MR-linac Based on “First-In-Man” Treatments
title_sort evaluation of online plan adaptation strategies for the 1.5t mr-linac based on “first-in-man” treatments
topic Medical Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988167/
https://www.ncbi.nlm.nih.gov/pubmed/29876153
http://dx.doi.org/10.7759/cureus.2431
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