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Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis

The transcription factors GATA4, GATA5 and GATA6 play important roles in heart muscle differentiation. The data presented in this article are related to the research article entitled “Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesi...

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Autores principales: Afouda, Boni A., Lynch, Adam T., de Paiva Alves, Eduardo, Hoppler, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988223/
https://www.ncbi.nlm.nih.gov/pubmed/29876429
http://dx.doi.org/10.1016/j.dib.2018.01.005
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author Afouda, Boni A.
Lynch, Adam T.
de Paiva Alves, Eduardo
Hoppler, Stefan
author_facet Afouda, Boni A.
Lynch, Adam T.
de Paiva Alves, Eduardo
Hoppler, Stefan
author_sort Afouda, Boni A.
collection PubMed
description The transcription factors GATA4, GATA5 and GATA6 play important roles in heart muscle differentiation. The data presented in this article are related to the research article entitled “Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis” (Afouda et al., 2017) [1]. The present study identifies genes regulated by these individual cardiogenic GATA factors using genome-wide transcriptomics analysis. We have presented genes that are specifically regulated by each of them, as well those regulated by either of them. The gene ontology terms (GO) associated with the genes differentially affected are also presented. The data set will allow further investigations on the gene regulatory network downstream of individual cardiogenic GATA factors during cardiac muscle formation.
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spelling pubmed-59882232018-06-06 Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis Afouda, Boni A. Lynch, Adam T. de Paiva Alves, Eduardo Hoppler, Stefan Data Brief Genetics, Genomics and Molecular Biology The transcription factors GATA4, GATA5 and GATA6 play important roles in heart muscle differentiation. The data presented in this article are related to the research article entitled “Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis” (Afouda et al., 2017) [1]. The present study identifies genes regulated by these individual cardiogenic GATA factors using genome-wide transcriptomics analysis. We have presented genes that are specifically regulated by each of them, as well those regulated by either of them. The gene ontology terms (GO) associated with the genes differentially affected are also presented. The data set will allow further investigations on the gene regulatory network downstream of individual cardiogenic GATA factors during cardiac muscle formation. Elsevier 2018-01-17 /pmc/articles/PMC5988223/ /pubmed/29876429 http://dx.doi.org/10.1016/j.dib.2018.01.005 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Genetics, Genomics and Molecular Biology
Afouda, Boni A.
Lynch, Adam T.
de Paiva Alves, Eduardo
Hoppler, Stefan
Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis
title Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis
title_full Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis
title_fullStr Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis
title_full_unstemmed Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis
title_short Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis
title_sort genome-wide transcriptomics analysis of genes regulated by gata4, 5 and 6 during cardiomyogenesis in xenopus laevis
topic Genetics, Genomics and Molecular Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988223/
https://www.ncbi.nlm.nih.gov/pubmed/29876429
http://dx.doi.org/10.1016/j.dib.2018.01.005
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