Data on differentially expressed miRNAs in dogs infected with Leishmania infantum

This paper contains data on differentially expressed miRNAs in peripheral blood mononuclear cells (PBMC) of dogs naturally infected by Leishmania (L.) infantum compared to healthy dogs. In recent years, studies with miRNAs have shown that these molecules play a critical role in the regulation and fu...

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Detalles Bibliográficos
Autores principales: Bragato, Jaqueline Poleto, Melo, Larissa Martins, Venturin, Gabriela Lovizutto, Rebech, Gabriela Torres, Garcia, Leandro Encarnação, Lopes, Flavia Lombardi, de Lima, Valéria Marçal Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Veterinary Science and Veterinary Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988227/
https://www.ncbi.nlm.nih.gov/pubmed/29876389
http://dx.doi.org/10.1016/j.dib.2018.01.007
Descripción
Sumario:This paper contains data on differentially expressed miRNAs in peripheral blood mononuclear cells (PBMC) of dogs naturally infected by Leishmania (L.) infantum compared to healthy dogs. In recent years, studies with miRNAs have shown that these molecules play a critical role in the regulation and function of immune response.Differentially expressed miRNAs were identified by microarray, validated by real time PCR and compared with parasite load in the dogs. Targets and pathways were analyzed using the Ingenuity Pathway Analysis program.

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