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A pharmaco-metabolomics approach in a clinical trial of ALS: Identification of predictive markers of progression
There is an urgent and unmet need for accurate biomarkers in Amyotrophic Lateral Sclerosis. A pharmaco-metabolomics study was conducted using plasma samples from the TRO19622 (olesoxime) trial to assess the link between early metabolomic profiles and clinical outcomes. Patients included in this tria...
Autores principales: | Blasco, Hélène, Patin, Franck, Descat, Amandine, Garçon, Guillaume, Corcia, Philippe, Gelé, Patrick, Lenglet, Timothée, Bede, Peter, Meininger, Vincent, Devos, David, Gossens, Jean François, Pradat, Pierre-François |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988280/ https://www.ncbi.nlm.nih.gov/pubmed/29870556 http://dx.doi.org/10.1371/journal.pone.0198116 |
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