The PH domain from the Toxoplasma gondii PH-containing protein-1 (TgPH1) serves as an ectopic reporter of phosphatidylinositol 3-phosphate in mammalian cells

Phosphoinositide (PtdInsP) lipids recruit effector proteins to membranes to mediate a variety of functions including signal transduction and membrane trafficking. Each PtdInsP binds to a specific set of effectors through characteristic protein domains such as the PH, FYVE and PX domains. Domains wit...

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Detalles Bibliográficos
Autores principales: Chintaluri, Krishna, Goulden, Brady D., Celmenza, Camilyn, Saffi, Golam, Miraglia, Emily, Hammond, Gerald R. V., Botelho, Roberto J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988325/
https://www.ncbi.nlm.nih.gov/pubmed/29870544
http://dx.doi.org/10.1371/journal.pone.0198454

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