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Membrane-associated human tyrosinase is an enzymatically active monomeric glycoprotein

Human tyrosinase (hTyr) is a Type 1 membrane bound glycoenzyme that catalyzes the initial and rate-limiting steps of melanin production in the melanosome. Mutations in the Tyr gene are linked to oculocutaneous albinism type 1 (OCA1), an autosomal recessive disorder. Currently, the application of enz...

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Detalles Bibliográficos
Autores principales:	Kus, Nicole J., Dolinska, Monika B., Young, Kenneth L., Dimitriadis, Emilios K., Wingfield, Paul T., Sergeev, Yuri V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988326/ https://www.ncbi.nlm.nih.gov/pubmed/29870551 http://dx.doi.org/10.1371/journal.pone.0198247

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