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Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin

In this article, we report a small RNA data set obtained from human T cell acute leukemia Jurkat cells, which were treated with the universal apoptotic agent camptothecin. Based on the Annexin-V labeling pattern, we sorted two Jurkat subpopulations in treated cells: one that is sensitive to the drug...

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Detalles Bibliográficos
Autores principales: Cosacak, Mehmet Ilyas, Erdogan, Ipek, Nalbant, Ayten, Akgul, Bunyamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988338/
https://www.ncbi.nlm.nih.gov/pubmed/29876408
http://dx.doi.org/10.1016/j.dib.2018.01.050
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author Cosacak, Mehmet Ilyas
Erdogan, Ipek
Nalbant, Ayten
Akgul, Bunyamin
author_facet Cosacak, Mehmet Ilyas
Erdogan, Ipek
Nalbant, Ayten
Akgul, Bunyamin
author_sort Cosacak, Mehmet Ilyas
collection PubMed
description In this article, we report a small RNA data set obtained from human T cell acute leukemia Jurkat cells, which were treated with the universal apoptotic agent camptothecin. Based on the Annexin-V labeling pattern, we sorted two Jurkat subpopulations in treated cells: one that is sensitive to the drug and the other being relatively more resistant. We report new original data that include the frequency of tRNA-derived fragments (tRF) in drug-sensitive and resistant cells. We also present partially analyzed data to show the origin of reads on tRNAs as well as the borders of the fragments. We believe that this data can benefit the science community working in the field of tRF and/or apoptosis.
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spelling pubmed-59883382018-06-06 Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin Cosacak, Mehmet Ilyas Erdogan, Ipek Nalbant, Ayten Akgul, Bunyamin Data Brief Cell biology In this article, we report a small RNA data set obtained from human T cell acute leukemia Jurkat cells, which were treated with the universal apoptotic agent camptothecin. Based on the Annexin-V labeling pattern, we sorted two Jurkat subpopulations in treated cells: one that is sensitive to the drug and the other being relatively more resistant. We report new original data that include the frequency of tRNA-derived fragments (tRF) in drug-sensitive and resistant cells. We also present partially analyzed data to show the origin of reads on tRNAs as well as the borders of the fragments. We believe that this data can benefit the science community working in the field of tRF and/or apoptosis. Elsevier 2018-02-03 /pmc/articles/PMC5988338/ /pubmed/29876408 http://dx.doi.org/10.1016/j.dib.2018.01.050 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Cell biology
Cosacak, Mehmet Ilyas
Erdogan, Ipek
Nalbant, Ayten
Akgul, Bunyamin
Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin
title Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin
title_full Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin
title_fullStr Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin
title_full_unstemmed Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin
title_short Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin
title_sort small rna data set that includes trna-derived fragments from jurkat cells treated with camptothecin
topic Cell biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988338/
https://www.ncbi.nlm.nih.gov/pubmed/29876408
http://dx.doi.org/10.1016/j.dib.2018.01.050
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