Cargando…
Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin
In this article, we report a small RNA data set obtained from human T cell acute leukemia Jurkat cells, which were treated with the universal apoptotic agent camptothecin. Based on the Annexin-V labeling pattern, we sorted two Jurkat subpopulations in treated cells: one that is sensitive to the drug...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988338/ https://www.ncbi.nlm.nih.gov/pubmed/29876408 http://dx.doi.org/10.1016/j.dib.2018.01.050 |
_version_ | 1783329267157827584 |
---|---|
author | Cosacak, Mehmet Ilyas Erdogan, Ipek Nalbant, Ayten Akgul, Bunyamin |
author_facet | Cosacak, Mehmet Ilyas Erdogan, Ipek Nalbant, Ayten Akgul, Bunyamin |
author_sort | Cosacak, Mehmet Ilyas |
collection | PubMed |
description | In this article, we report a small RNA data set obtained from human T cell acute leukemia Jurkat cells, which were treated with the universal apoptotic agent camptothecin. Based on the Annexin-V labeling pattern, we sorted two Jurkat subpopulations in treated cells: one that is sensitive to the drug and the other being relatively more resistant. We report new original data that include the frequency of tRNA-derived fragments (tRF) in drug-sensitive and resistant cells. We also present partially analyzed data to show the origin of reads on tRNAs as well as the borders of the fragments. We believe that this data can benefit the science community working in the field of tRF and/or apoptosis. |
format | Online Article Text |
id | pubmed-5988338 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-59883382018-06-06 Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin Cosacak, Mehmet Ilyas Erdogan, Ipek Nalbant, Ayten Akgul, Bunyamin Data Brief Cell biology In this article, we report a small RNA data set obtained from human T cell acute leukemia Jurkat cells, which were treated with the universal apoptotic agent camptothecin. Based on the Annexin-V labeling pattern, we sorted two Jurkat subpopulations in treated cells: one that is sensitive to the drug and the other being relatively more resistant. We report new original data that include the frequency of tRNA-derived fragments (tRF) in drug-sensitive and resistant cells. We also present partially analyzed data to show the origin of reads on tRNAs as well as the borders of the fragments. We believe that this data can benefit the science community working in the field of tRF and/or apoptosis. Elsevier 2018-02-03 /pmc/articles/PMC5988338/ /pubmed/29876408 http://dx.doi.org/10.1016/j.dib.2018.01.050 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Cell biology Cosacak, Mehmet Ilyas Erdogan, Ipek Nalbant, Ayten Akgul, Bunyamin Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin |
title | Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin |
title_full | Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin |
title_fullStr | Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin |
title_full_unstemmed | Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin |
title_short | Small RNA data set that includes tRNA-derived fragments from Jurkat cells treated with camptothecin |
title_sort | small rna data set that includes trna-derived fragments from jurkat cells treated with camptothecin |
topic | Cell biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988338/ https://www.ncbi.nlm.nih.gov/pubmed/29876408 http://dx.doi.org/10.1016/j.dib.2018.01.050 |
work_keys_str_mv | AT cosacakmehmetilyas smallrnadatasetthatincludestrnaderivedfragmentsfromjurkatcellstreatedwithcamptothecin AT erdoganipek smallrnadatasetthatincludestrnaderivedfragmentsfromjurkatcellstreatedwithcamptothecin AT nalbantayten smallrnadatasetthatincludestrnaderivedfragmentsfromjurkatcellstreatedwithcamptothecin AT akgulbunyamin smallrnadatasetthatincludestrnaderivedfragmentsfromjurkatcellstreatedwithcamptothecin |