Re-salvage MRI-guided Focal High-dose-rate Brachytherapy for Locally Recurrent Prostate Cancer

Prostate cancer recurrences are common, even with twenty-first-century primary prostate cancer treatment modalities. The most common salvage treatment is (delayed) hormonal therapy, which is often associated with serious side-effects. Due to the risk of significant toxicity, whole-gland targeted sal...

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Autores principales: Van Son, Marieke J, Peters, Max, Moerland, Marinus A, Noteboom, Juus L, Eppinga, Wietse S, Davila Fajardo, Raquel, Lagendijk, Jan, Van der Voort van Zyp, Jochem R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Medical Physics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988341/
https://www.ncbi.nlm.nih.gov/pubmed/29876151
http://dx.doi.org/10.7759/cureus.2429
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author Van Son, Marieke J
Peters, Max
Moerland, Marinus A
Noteboom, Juus L
Eppinga, Wietse S
Davila Fajardo, Raquel
Lagendijk, Jan
Van der Voort van Zyp, Jochem R
author_facet Van Son, Marieke J
Peters, Max
Moerland, Marinus A
Noteboom, Juus L
Eppinga, Wietse S
Davila Fajardo, Raquel
Lagendijk, Jan
Van der Voort van Zyp, Jochem R
author_sort Van Son, Marieke J
collection PubMed
description Prostate cancer recurrences are common, even with twenty-first-century primary prostate cancer treatment modalities. The most common salvage treatment is (delayed) hormonal therapy, which is often associated with serious side-effects. Due to the risk of significant toxicity, whole-gland targeted salvage treatments remain unpopular. Consequently, developments in focal therapies have arisen. Magnetic resonance imaging (MRI)-guided focal salvage high-dose-rate brachytherapy (HDR-BT) is a novel treatment aiming for minimal toxicity in recurrent prostate cancer patients. Repeating focal treatment could, therefore, be possible in case of post-salvage recurrence. We report the case of a 77-year-old man who underwent repeat focal HDR-BT.
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spelling pubmed-59883412018-06-06 Re-salvage MRI-guided Focal High-dose-rate Brachytherapy for Locally Recurrent Prostate Cancer Van Son, Marieke J Peters, Max Moerland, Marinus A Noteboom, Juus L Eppinga, Wietse S Davila Fajardo, Raquel Lagendijk, Jan Van der Voort van Zyp, Jochem R Cureus Medical Physics Prostate cancer recurrences are common, even with twenty-first-century primary prostate cancer treatment modalities. The most common salvage treatment is (delayed) hormonal therapy, which is often associated with serious side-effects. Due to the risk of significant toxicity, whole-gland targeted salvage treatments remain unpopular. Consequently, developments in focal therapies have arisen. Magnetic resonance imaging (MRI)-guided focal salvage high-dose-rate brachytherapy (HDR-BT) is a novel treatment aiming for minimal toxicity in recurrent prostate cancer patients. Repeating focal treatment could, therefore, be possible in case of post-salvage recurrence. We report the case of a 77-year-old man who underwent repeat focal HDR-BT. Cureus 2018-04-05 /pmc/articles/PMC5988341/ /pubmed/29876151 http://dx.doi.org/10.7759/cureus.2429 Text en Copyright © 2018, Van Son et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Medical Physics
Van Son, Marieke J
Peters, Max
Moerland, Marinus A
Noteboom, Juus L
Eppinga, Wietse S
Davila Fajardo, Raquel
Lagendijk, Jan
Van der Voort van Zyp, Jochem R
Re-salvage MRI-guided Focal High-dose-rate Brachytherapy for Locally Recurrent Prostate Cancer
title Re-salvage MRI-guided Focal High-dose-rate Brachytherapy for Locally Recurrent Prostate Cancer
title_full Re-salvage MRI-guided Focal High-dose-rate Brachytherapy for Locally Recurrent Prostate Cancer
title_fullStr Re-salvage MRI-guided Focal High-dose-rate Brachytherapy for Locally Recurrent Prostate Cancer
title_full_unstemmed Re-salvage MRI-guided Focal High-dose-rate Brachytherapy for Locally Recurrent Prostate Cancer
title_short Re-salvage MRI-guided Focal High-dose-rate Brachytherapy for Locally Recurrent Prostate Cancer
title_sort re-salvage mri-guided focal high-dose-rate brachytherapy for locally recurrent prostate cancer
topic Medical Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988341/
https://www.ncbi.nlm.nih.gov/pubmed/29876151
http://dx.doi.org/10.7759/cureus.2429
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