Surface Plasmon Resonance kinetic analysis of the interaction between G-quadruplex nucleic acids and an anti-G-quadruplex monoclonal antibody

BACKGROUND: G-quadruplexes (G4s) are nucleic acids secondary structures formed in guanine-rich sequences. Anti-G4 antibodies represent a tool for the direct investigation of G4s in cells. Surface Plasmon Resonance (SPR) is a highly sensitive technology, suitable for assessing the affinity between bi...

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Detalles Bibliográficos
Autores principales: Lago, Sara, Nadai, Matteo, Rossetto, Monica, Richter, Sara N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988565/
https://www.ncbi.nlm.nih.gov/pubmed/29524541
http://dx.doi.org/10.1016/j.bbagen.2018.03.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988565/
https://www.ncbi.nlm.nih.gov/pubmed/29524541
http://dx.doi.org/10.1016/j.bbagen.2018.03.002

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