Cargando…
Selective regulation of osteoclast adhesion and spreading by PLCγ/PKCα-PKCδ/RhoA-Rac1 signaling
Bone resorption by multinucleated osteoclasts is a multistep process involving adhesion to the bone matrix, migration to resorption sites, and formation of sealing zones and ruffled borders. Macrophage colony-stimulating factor (M-CSF) and osteopontin (OPN) have been shown to be involved in the bone...
Autores principales: | Kim, Jin-Man, Lee, Kyunghee, Jeong, Daewon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988577/ https://www.ncbi.nlm.nih.gov/pubmed/29301608 http://dx.doi.org/10.5483/BMBRep.2018.51.5.198 |
Ejemplares similares
-
Cholecystokinin-Mediated RhoGDI Phosphorylation via PKCα Promotes both RhoA and Rac1 Signaling
por: Sabbatini, Maria Eugenia, et al.
Publicado: (2013) -
Specific targeting of PKCδ suppresses osteoclast differentiation by accelerating proteolysis of membrane-bound macrophage colony-stimulating factor receptor
por: Kim, Mi Yeong, et al.
Publicado: (2019) -
PKCα and PKCδ: Friends and Rivals
por: Black, Jennifer D., et al.
Publicado: (2022) -
PKCε Phosphorylates and Mediates the Cell Membrane Localization of RhoA
por: Su, Tizhi, et al.
Publicado: (2013) -
PKCδ Localization at the Membrane Increases Matrix Traction Force Dependent on PLCγ1/EGFR Signaling
por: Jamison, Joshua, et al.
Publicado: (2013)