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Introducing the Affinity Binder Knockdown Initiative⿿A public⿿private partnership for validation of affinity reagents

The newly launched Affinity Binder Knockdown Initiative encourages antibody suppliers and users to join this public⿿private partnership, which uses crowdsourcing to collect characterization data on antibodies. Researchers are asked to share validation data from experiments where gene-editing techniq...

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Detalles Bibliográficos
Autores principales: Alm, Tove, Lundberg, Emma, Uhlén, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988587/
https://www.ncbi.nlm.nih.gov/pubmed/29900101
http://dx.doi.org/10.1016/j.euprot.2016.01.002
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author Alm, Tove
Lundberg, Emma
Uhlén, Mathias
author_facet Alm, Tove
Lundberg, Emma
Uhlén, Mathias
author_sort Alm, Tove
collection PubMed
description The newly launched Affinity Binder Knockdown Initiative encourages antibody suppliers and users to join this public⿿private partnership, which uses crowdsourcing to collect characterization data on antibodies. Researchers are asked to share validation data from experiments where gene-editing techniques (such as siRNA or CRISPR) have been used to verify antibody binding. The initiative is launched under the aegis of Antibodypedia, a database designed to allow comparisons and scoring of publicly available antibodies towards human protein targets. What is known about an antibody is the foundation of the scoring and ranking system in Antibodypedia.
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spelling pubmed-59885872018-06-13 Introducing the Affinity Binder Knockdown Initiative⿿A public⿿private partnership for validation of affinity reagents Alm, Tove Lundberg, Emma Uhlén, Mathias EuPA Open Proteom Special Section: Proceedings of the 9th Annual EuPA Congress “Proteomics - Back to the Future” (June 23 - 28, 2015, Milano, Italy) The newly launched Affinity Binder Knockdown Initiative encourages antibody suppliers and users to join this public⿿private partnership, which uses crowdsourcing to collect characterization data on antibodies. Researchers are asked to share validation data from experiments where gene-editing techniques (such as siRNA or CRISPR) have been used to verify antibody binding. The initiative is launched under the aegis of Antibodypedia, a database designed to allow comparisons and scoring of publicly available antibodies towards human protein targets. What is known about an antibody is the foundation of the scoring and ranking system in Antibodypedia. Elsevier 2016-01-07 /pmc/articles/PMC5988587/ /pubmed/29900101 http://dx.doi.org/10.1016/j.euprot.2016.01.002 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Special Section: Proceedings of the 9th Annual EuPA Congress “Proteomics - Back to the Future” (June 23 - 28, 2015, Milano, Italy)
Alm, Tove
Lundberg, Emma
Uhlén, Mathias
Introducing the Affinity Binder Knockdown Initiative⿿A public⿿private partnership for validation of affinity reagents
title Introducing the Affinity Binder Knockdown Initiative⿿A public⿿private partnership for validation of affinity reagents
title_full Introducing the Affinity Binder Knockdown Initiative⿿A public⿿private partnership for validation of affinity reagents
title_fullStr Introducing the Affinity Binder Knockdown Initiative⿿A public⿿private partnership for validation of affinity reagents
title_full_unstemmed Introducing the Affinity Binder Knockdown Initiative⿿A public⿿private partnership for validation of affinity reagents
title_short Introducing the Affinity Binder Knockdown Initiative⿿A public⿿private partnership for validation of affinity reagents
title_sort introducing the affinity binder knockdown initiative⿿a public⿿private partnership for validation of affinity reagents
topic Special Section: Proceedings of the 9th Annual EuPA Congress “Proteomics - Back to the Future” (June 23 - 28, 2015, Milano, Italy)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988587/
https://www.ncbi.nlm.nih.gov/pubmed/29900101
http://dx.doi.org/10.1016/j.euprot.2016.01.002
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