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Introducing the Affinity Binder Knockdown InitiativeA publicprivate partnership for validation of affinity reagents
The newly launched Affinity Binder Knockdown Initiative encourages antibody suppliers and users to join this publicprivate partnership, which uses crowdsourcing to collect characterization data on antibodies. Researchers are asked to share validation data from experiments where gene-editing techniq...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988587/ https://www.ncbi.nlm.nih.gov/pubmed/29900101 http://dx.doi.org/10.1016/j.euprot.2016.01.002 |
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author | Alm, Tove Lundberg, Emma Uhlén, Mathias |
author_facet | Alm, Tove Lundberg, Emma Uhlén, Mathias |
author_sort | Alm, Tove |
collection | PubMed |
description | The newly launched Affinity Binder Knockdown Initiative encourages antibody suppliers and users to join this publicprivate partnership, which uses crowdsourcing to collect characterization data on antibodies. Researchers are asked to share validation data from experiments where gene-editing techniques (such as siRNA or CRISPR) have been used to verify antibody binding. The initiative is launched under the aegis of Antibodypedia, a database designed to allow comparisons and scoring of publicly available antibodies towards human protein targets. What is known about an antibody is the foundation of the scoring and ranking system in Antibodypedia. |
format | Online Article Text |
id | pubmed-5988587 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-59885872018-06-13 Introducing the Affinity Binder Knockdown InitiativeA publicprivate partnership for validation of affinity reagents Alm, Tove Lundberg, Emma Uhlén, Mathias EuPA Open Proteom Special Section: Proceedings of the 9th Annual EuPA Congress “Proteomics - Back to the Future” (June 23 - 28, 2015, Milano, Italy) The newly launched Affinity Binder Knockdown Initiative encourages antibody suppliers and users to join this publicprivate partnership, which uses crowdsourcing to collect characterization data on antibodies. Researchers are asked to share validation data from experiments where gene-editing techniques (such as siRNA or CRISPR) have been used to verify antibody binding. The initiative is launched under the aegis of Antibodypedia, a database designed to allow comparisons and scoring of publicly available antibodies towards human protein targets. What is known about an antibody is the foundation of the scoring and ranking system in Antibodypedia. Elsevier 2016-01-07 /pmc/articles/PMC5988587/ /pubmed/29900101 http://dx.doi.org/10.1016/j.euprot.2016.01.002 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Special Section: Proceedings of the 9th Annual EuPA Congress “Proteomics - Back to the Future” (June 23 - 28, 2015, Milano, Italy) Alm, Tove Lundberg, Emma Uhlén, Mathias Introducing the Affinity Binder Knockdown InitiativeA publicprivate partnership for validation of affinity reagents |
title | Introducing the Affinity Binder Knockdown InitiativeA publicprivate partnership for validation of affinity reagents |
title_full | Introducing the Affinity Binder Knockdown InitiativeA publicprivate partnership for validation of affinity reagents |
title_fullStr | Introducing the Affinity Binder Knockdown InitiativeA publicprivate partnership for validation of affinity reagents |
title_full_unstemmed | Introducing the Affinity Binder Knockdown InitiativeA publicprivate partnership for validation of affinity reagents |
title_short | Introducing the Affinity Binder Knockdown InitiativeA publicprivate partnership for validation of affinity reagents |
title_sort | introducing the affinity binder knockdown initiativea publicprivate partnership for validation of affinity reagents |
topic | Special Section: Proceedings of the 9th Annual EuPA Congress “Proteomics - Back to the Future” (June 23 - 28, 2015, Milano, Italy) |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988587/ https://www.ncbi.nlm.nih.gov/pubmed/29900101 http://dx.doi.org/10.1016/j.euprot.2016.01.002 |
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