APX3330 Promotes Neurorestorative Effects after Stroke in Type One Diabetic Rats

APX3330 is a selective inhibitor of APE1/Ref-1 redox activity. In this study, we investigate the therapeutic effects and underlying mechanisms of APX3330 treatment in type one diabetes mellitus (T1DM) stroke rats. Adult male Wistar rats were induced with T1DM and subjected to transient middle cerebr...

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Detalles Bibliográficos
Autores principales: Yan, Tao, Venkat, Poornima, Chopp, Michael, Zacharek, Alex, Yu, Peng, Ning, Ruizhuo, Qiao, Xiaoxi, Kelley, Mark R., Chen, Jieli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2018
Materias:
Orginal Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988600/
https://www.ncbi.nlm.nih.gov/pubmed/29896433
http://dx.doi.org/10.14336/AD.2017.1130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988600/
https://www.ncbi.nlm.nih.gov/pubmed/29896433
http://dx.doi.org/10.14336/AD.2017.1130

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