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Third-generation Sequencing Reveals Extensive Polycistronism and Transcriptional Overlapping in a Baculovirus

The Autographa californica multiple nucleopolyhedrovirus (AcMNPV) is an insect-pathogen baculovirus. In this study, we applied the Oxford Nanopore Technologies platform for the analysis of the polyadenylated fraction of the viral transcriptome using both cDNA and direct RNA sequencing methods. We id...

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Detalles Bibliográficos
Autores principales: Moldován, Norbert, Tombácz, Dóra, Szűcs, Attila, Csabai, Zsolt, Balázs, Zsolt, Kis, Emese, Molnár, Judit, Boldogkői, Zsolt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988703/
https://www.ncbi.nlm.nih.gov/pubmed/29872099
http://dx.doi.org/10.1038/s41598-018-26955-8