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Use of Hemagglutinin Stem Probes Demonstrate Prevalence of Broadly Reactive Group 1 Influenza Antibodies in Human Sera
A better understanding of the seroprevalence and specificity of influenza HA stem-directed broadly neutralizing antibodies (bNAbs) in the human population could significantly inform influenza vaccine design efforts. Here, we utilized probes comprising headless, HA stabilized stem (SS) to determine t...
Autores principales: | Yassine, Hadi M., McTamney, Patrick M., Boyington, Jeffery C., Ruckwardt, Tracy J., Crank, Michelle C., Smatti, Maria K., Ledgerwood, Julie E., Graham, Barney S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988737/ https://www.ncbi.nlm.nih.gov/pubmed/29872070 http://dx.doi.org/10.1038/s41598-018-26538-7 |
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