Cargando…

Factors associated with late presentation for HIV care in a single Belgian reference center: 2006–2017

Late presentation for HIV care is a major issue and the cause of higher morbidity, mortality and transmission. In this regard, we analyzed the characteristics of patients presenting for care at our center from January 2006 to July 2017 (n = 687). The majority of the studied population was of African...

Descripción completa

Detalles Bibliográficos
Autores principales: Darcis, Gilles, Lambert, Iseult, Sauvage, Anne-Sophie, Frippiat, Frédéric, Meuris, Christelle, Uurlings, Françoise, Lecomte, Marianne, Léonard, Philippe, Giot, Jean-Baptiste, Fombellida, Karine, Vaira, Dolores, Moutschen, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988738/
https://www.ncbi.nlm.nih.gov/pubmed/29872068
http://dx.doi.org/10.1038/s41598-018-26852-0
_version_ 1783329337437585408
author Darcis, Gilles
Lambert, Iseult
Sauvage, Anne-Sophie
Frippiat, Frédéric
Meuris, Christelle
Uurlings, Françoise
Lecomte, Marianne
Léonard, Philippe
Giot, Jean-Baptiste
Fombellida, Karine
Vaira, Dolores
Moutschen, Michel
author_facet Darcis, Gilles
Lambert, Iseult
Sauvage, Anne-Sophie
Frippiat, Frédéric
Meuris, Christelle
Uurlings, Françoise
Lecomte, Marianne
Léonard, Philippe
Giot, Jean-Baptiste
Fombellida, Karine
Vaira, Dolores
Moutschen, Michel
author_sort Darcis, Gilles
collection PubMed
description Late presentation for HIV care is a major issue and the cause of higher morbidity, mortality and transmission. In this regard, we analyzed the characteristics of patients presenting for care at our center from January 2006 to July 2017 (n = 687). The majority of the studied population was of African origin (54.3%) with heterosexual women representing the main group (n = 292; 42.5%). 44% of the patients were late presenters (LP) (presenting for care with CD4 T cells <350/mm(3) or an AIDS defining event) and 24% were late presenters with advanced disease (LP-AD) (presenting for care with CD4 T cells <200/mm(3) or an AIDS defining event). A very high risk of being LP and LP-AD was associated with Sub-Saharan origin (OR 3.4 and 2.6 respectively). Other factors independently associated with LP or LP-AD were age (OR 1.3), male gender (OR 2.0 and 1.5 respectively) and heterosexual route of transmission (OR 2.4 and 2.3 respectively). A significant increase in HIV screening without forgetting those groups would contribute to earlier HIV diagnosis, a key element to end the HIV epidemic. To achieve this goal, addressing the specific hurdles to HIV testing in the migrant population is critical.
format Online
Article
Text
id pubmed-5988738
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-59887382018-06-20 Factors associated with late presentation for HIV care in a single Belgian reference center: 2006–2017 Darcis, Gilles Lambert, Iseult Sauvage, Anne-Sophie Frippiat, Frédéric Meuris, Christelle Uurlings, Françoise Lecomte, Marianne Léonard, Philippe Giot, Jean-Baptiste Fombellida, Karine Vaira, Dolores Moutschen, Michel Sci Rep Article Late presentation for HIV care is a major issue and the cause of higher morbidity, mortality and transmission. In this regard, we analyzed the characteristics of patients presenting for care at our center from January 2006 to July 2017 (n = 687). The majority of the studied population was of African origin (54.3%) with heterosexual women representing the main group (n = 292; 42.5%). 44% of the patients were late presenters (LP) (presenting for care with CD4 T cells <350/mm(3) or an AIDS defining event) and 24% were late presenters with advanced disease (LP-AD) (presenting for care with CD4 T cells <200/mm(3) or an AIDS defining event). A very high risk of being LP and LP-AD was associated with Sub-Saharan origin (OR 3.4 and 2.6 respectively). Other factors independently associated with LP or LP-AD were age (OR 1.3), male gender (OR 2.0 and 1.5 respectively) and heterosexual route of transmission (OR 2.4 and 2.3 respectively). A significant increase in HIV screening without forgetting those groups would contribute to earlier HIV diagnosis, a key element to end the HIV epidemic. To achieve this goal, addressing the specific hurdles to HIV testing in the migrant population is critical. Nature Publishing Group UK 2018-06-05 /pmc/articles/PMC5988738/ /pubmed/29872068 http://dx.doi.org/10.1038/s41598-018-26852-0 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Darcis, Gilles
Lambert, Iseult
Sauvage, Anne-Sophie
Frippiat, Frédéric
Meuris, Christelle
Uurlings, Françoise
Lecomte, Marianne
Léonard, Philippe
Giot, Jean-Baptiste
Fombellida, Karine
Vaira, Dolores
Moutschen, Michel
Factors associated with late presentation for HIV care in a single Belgian reference center: 2006–2017
title Factors associated with late presentation for HIV care in a single Belgian reference center: 2006–2017
title_full Factors associated with late presentation for HIV care in a single Belgian reference center: 2006–2017
title_fullStr Factors associated with late presentation for HIV care in a single Belgian reference center: 2006–2017
title_full_unstemmed Factors associated with late presentation for HIV care in a single Belgian reference center: 2006–2017
title_short Factors associated with late presentation for HIV care in a single Belgian reference center: 2006–2017
title_sort factors associated with late presentation for hiv care in a single belgian reference center: 2006–2017
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988738/
https://www.ncbi.nlm.nih.gov/pubmed/29872068
http://dx.doi.org/10.1038/s41598-018-26852-0
work_keys_str_mv AT darcisgilles factorsassociatedwithlatepresentationforhivcareinasinglebelgianreferencecenter20062017
AT lambertiseult factorsassociatedwithlatepresentationforhivcareinasinglebelgianreferencecenter20062017
AT sauvageannesophie factorsassociatedwithlatepresentationforhivcareinasinglebelgianreferencecenter20062017
AT frippiatfrederic factorsassociatedwithlatepresentationforhivcareinasinglebelgianreferencecenter20062017
AT meurischristelle factorsassociatedwithlatepresentationforhivcareinasinglebelgianreferencecenter20062017
AT uurlingsfrancoise factorsassociatedwithlatepresentationforhivcareinasinglebelgianreferencecenter20062017
AT lecomtemarianne factorsassociatedwithlatepresentationforhivcareinasinglebelgianreferencecenter20062017
AT leonardphilippe factorsassociatedwithlatepresentationforhivcareinasinglebelgianreferencecenter20062017
AT giotjeanbaptiste factorsassociatedwithlatepresentationforhivcareinasinglebelgianreferencecenter20062017
AT fombellidakarine factorsassociatedwithlatepresentationforhivcareinasinglebelgianreferencecenter20062017
AT vairadolores factorsassociatedwithlatepresentationforhivcareinasinglebelgianreferencecenter20062017
AT moutschenmichel factorsassociatedwithlatepresentationforhivcareinasinglebelgianreferencecenter20062017