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Factors associated with late presentation for HIV care in a single Belgian reference center: 2006–2017
Late presentation for HIV care is a major issue and the cause of higher morbidity, mortality and transmission. In this regard, we analyzed the characteristics of patients presenting for care at our center from January 2006 to July 2017 (n = 687). The majority of the studied population was of African...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988738/ https://www.ncbi.nlm.nih.gov/pubmed/29872068 http://dx.doi.org/10.1038/s41598-018-26852-0 |
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author | Darcis, Gilles Lambert, Iseult Sauvage, Anne-Sophie Frippiat, Frédéric Meuris, Christelle Uurlings, Françoise Lecomte, Marianne Léonard, Philippe Giot, Jean-Baptiste Fombellida, Karine Vaira, Dolores Moutschen, Michel |
author_facet | Darcis, Gilles Lambert, Iseult Sauvage, Anne-Sophie Frippiat, Frédéric Meuris, Christelle Uurlings, Françoise Lecomte, Marianne Léonard, Philippe Giot, Jean-Baptiste Fombellida, Karine Vaira, Dolores Moutschen, Michel |
author_sort | Darcis, Gilles |
collection | PubMed |
description | Late presentation for HIV care is a major issue and the cause of higher morbidity, mortality and transmission. In this regard, we analyzed the characteristics of patients presenting for care at our center from January 2006 to July 2017 (n = 687). The majority of the studied population was of African origin (54.3%) with heterosexual women representing the main group (n = 292; 42.5%). 44% of the patients were late presenters (LP) (presenting for care with CD4 T cells <350/mm(3) or an AIDS defining event) and 24% were late presenters with advanced disease (LP-AD) (presenting for care with CD4 T cells <200/mm(3) or an AIDS defining event). A very high risk of being LP and LP-AD was associated with Sub-Saharan origin (OR 3.4 and 2.6 respectively). Other factors independently associated with LP or LP-AD were age (OR 1.3), male gender (OR 2.0 and 1.5 respectively) and heterosexual route of transmission (OR 2.4 and 2.3 respectively). A significant increase in HIV screening without forgetting those groups would contribute to earlier HIV diagnosis, a key element to end the HIV epidemic. To achieve this goal, addressing the specific hurdles to HIV testing in the migrant population is critical. |
format | Online Article Text |
id | pubmed-5988738 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-59887382018-06-20 Factors associated with late presentation for HIV care in a single Belgian reference center: 2006–2017 Darcis, Gilles Lambert, Iseult Sauvage, Anne-Sophie Frippiat, Frédéric Meuris, Christelle Uurlings, Françoise Lecomte, Marianne Léonard, Philippe Giot, Jean-Baptiste Fombellida, Karine Vaira, Dolores Moutschen, Michel Sci Rep Article Late presentation for HIV care is a major issue and the cause of higher morbidity, mortality and transmission. In this regard, we analyzed the characteristics of patients presenting for care at our center from January 2006 to July 2017 (n = 687). The majority of the studied population was of African origin (54.3%) with heterosexual women representing the main group (n = 292; 42.5%). 44% of the patients were late presenters (LP) (presenting for care with CD4 T cells <350/mm(3) or an AIDS defining event) and 24% were late presenters with advanced disease (LP-AD) (presenting for care with CD4 T cells <200/mm(3) or an AIDS defining event). A very high risk of being LP and LP-AD was associated with Sub-Saharan origin (OR 3.4 and 2.6 respectively). Other factors independently associated with LP or LP-AD were age (OR 1.3), male gender (OR 2.0 and 1.5 respectively) and heterosexual route of transmission (OR 2.4 and 2.3 respectively). A significant increase in HIV screening without forgetting those groups would contribute to earlier HIV diagnosis, a key element to end the HIV epidemic. To achieve this goal, addressing the specific hurdles to HIV testing in the migrant population is critical. Nature Publishing Group UK 2018-06-05 /pmc/articles/PMC5988738/ /pubmed/29872068 http://dx.doi.org/10.1038/s41598-018-26852-0 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Darcis, Gilles Lambert, Iseult Sauvage, Anne-Sophie Frippiat, Frédéric Meuris, Christelle Uurlings, Françoise Lecomte, Marianne Léonard, Philippe Giot, Jean-Baptiste Fombellida, Karine Vaira, Dolores Moutschen, Michel Factors associated with late presentation for HIV care in a single Belgian reference center: 2006–2017 |
title | Factors associated with late presentation for HIV care in a single Belgian reference center: 2006–2017 |
title_full | Factors associated with late presentation for HIV care in a single Belgian reference center: 2006–2017 |
title_fullStr | Factors associated with late presentation for HIV care in a single Belgian reference center: 2006–2017 |
title_full_unstemmed | Factors associated with late presentation for HIV care in a single Belgian reference center: 2006–2017 |
title_short | Factors associated with late presentation for HIV care in a single Belgian reference center: 2006–2017 |
title_sort | factors associated with late presentation for hiv care in a single belgian reference center: 2006–2017 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988738/ https://www.ncbi.nlm.nih.gov/pubmed/29872068 http://dx.doi.org/10.1038/s41598-018-26852-0 |
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