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Performing corneal crosslinking under local anaesthesia in patients with Down syndrome

PURPOSE: To report on the ability to perform corneal crosslinking (CXL) under local anaesthesia for the treatment of keratoconus in patients with Down syndrome. METHODS: Nine eyes of seven patients with both keratoconus and Down syndrome were scheduled for an epithelium-off CXL procedure under local...

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Autores principales: Soeters, Nienke, Bennen, Esmée, Wisse, Robert P. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988782/
https://www.ncbi.nlm.nih.gov/pubmed/28424993
http://dx.doi.org/10.1007/s10792-017-0535-1
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author Soeters, Nienke
Bennen, Esmée
Wisse, Robert P. L.
author_facet Soeters, Nienke
Bennen, Esmée
Wisse, Robert P. L.
author_sort Soeters, Nienke
collection PubMed
description PURPOSE: To report on the ability to perform corneal crosslinking (CXL) under local anaesthesia for the treatment of keratoconus in patients with Down syndrome. METHODS: Nine eyes of seven patients with both keratoconus and Down syndrome were scheduled for an epithelium-off CXL procedure under local anaesthesia. Exclusion criteria were a corneal thickness under 400 µm and the presence of corneal scars. A standardized clinical decision tool was used to estimate patient cooperation and the likelihood for a successful procedure under local rather than general anaesthesia. RESULTS: In seven eyes, the CXL was completed successfully. The treatment was aborted in two eyes due to insufficient corneal thickness (<400 µm) prior to ultraviolet-A irradiation, even after employing hypoosmolar riboflavin. No adverse events occurred post-operatively, except for one case of delayed epithelial healing (23 days). CONCLUSIONS: With a proper patient selection, CXL under local anaesthesia can be achieved in patients with Down syndrome.
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spelling pubmed-59887822018-06-12 Performing corneal crosslinking under local anaesthesia in patients with Down syndrome Soeters, Nienke Bennen, Esmée Wisse, Robert P. L. Int Ophthalmol Original Paper PURPOSE: To report on the ability to perform corneal crosslinking (CXL) under local anaesthesia for the treatment of keratoconus in patients with Down syndrome. METHODS: Nine eyes of seven patients with both keratoconus and Down syndrome were scheduled for an epithelium-off CXL procedure under local anaesthesia. Exclusion criteria were a corneal thickness under 400 µm and the presence of corneal scars. A standardized clinical decision tool was used to estimate patient cooperation and the likelihood for a successful procedure under local rather than general anaesthesia. RESULTS: In seven eyes, the CXL was completed successfully. The treatment was aborted in two eyes due to insufficient corneal thickness (<400 µm) prior to ultraviolet-A irradiation, even after employing hypoosmolar riboflavin. No adverse events occurred post-operatively, except for one case of delayed epithelial healing (23 days). CONCLUSIONS: With a proper patient selection, CXL under local anaesthesia can be achieved in patients with Down syndrome. Springer Netherlands 2017-04-19 2018 /pmc/articles/PMC5988782/ /pubmed/28424993 http://dx.doi.org/10.1007/s10792-017-0535-1 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Paper
Soeters, Nienke
Bennen, Esmée
Wisse, Robert P. L.
Performing corneal crosslinking under local anaesthesia in patients with Down syndrome
title Performing corneal crosslinking under local anaesthesia in patients with Down syndrome
title_full Performing corneal crosslinking under local anaesthesia in patients with Down syndrome
title_fullStr Performing corneal crosslinking under local anaesthesia in patients with Down syndrome
title_full_unstemmed Performing corneal crosslinking under local anaesthesia in patients with Down syndrome
title_short Performing corneal crosslinking under local anaesthesia in patients with Down syndrome
title_sort performing corneal crosslinking under local anaesthesia in patients with down syndrome
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988782/
https://www.ncbi.nlm.nih.gov/pubmed/28424993
http://dx.doi.org/10.1007/s10792-017-0535-1
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