An adenovirus serotype 2-vectored ebolavirus vaccine generates robust antibody and cell-mediated immune responses in mice and rhesus macaques

Ebolavirus vaccines based on several adenoviral vectors have been investigated in preclinical studies and clinical trials. The use of adenovirus serotype 2 as a vector for ebolavirus vaccine has not been reported. Herein, we generated rAd2-ZGP, a recombinant replication-incompetent adenovirus seroty...

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Detalles Bibliográficos
Autores principales: Feng, Yupeng, Li, Chufang, Hu, Peiyu, Wang, Qian, Zheng, Xuehua, Zhao, Yongkun, Shi, Yi, Yang, Songtao, Yi, Changhua, Feng, Ying, Wu, Chunxiu, Qu, Linbing, Xu, Wei, Li, Yao, Sun, Caijun, Gao, Fu Geroge, Xia, Xianzhu, Feng, Liqiang, Chen, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988821/
https://www.ncbi.nlm.nih.gov/pubmed/29872043
http://dx.doi.org/10.1038/s41426-018-0102-5

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