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Ccl2 deficiency protects against chronic renal injury in murine renovascular hypertension
Inflammation plays an important role in the pathogenesis of renal and cardiovascular disease in renovascular hypertension (RVH). Ccl2 is an important mediator of inflammation, and is induced within 24 hours following surgery to establish RVH in the murine 2 kidney 1 clip model, a time prior to onset...
Autores principales: | Kashyap, Sonu, Osman, Mazen, Ferguson, Christopher M., Nath, Meryl C., Roy, Bhaskar, Lien, Karen R., Nath, Karl A., Garovic, Vesna D., Lerman, Lilach O., Grande, Joseph P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988825/ https://www.ncbi.nlm.nih.gov/pubmed/29872089 http://dx.doi.org/10.1038/s41598-018-26870-y |
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