Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine

Acting downstream of many growth factors, extracellular signal-regulated kinase (ERK) plays a pivotal role in regulating cell proliferation and tumorigenesis, where its spatiotemporal dynamics, as well as its strength, determine cellular responses. Here, we uncover the ERK activity dynamics in intes...

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Detalles Bibliográficos
Autores principales: Muta, Yu, Fujita, Yoshihisa, Sumiyama, Kenta, Sakurai, Atsuro, Taketo, M. Mark, Chiba, Tsutomu, Seno, Hiroshi, Aoki, Kazuhiro, Matsuda, Michiyuki, Imajo, Masamichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988836/
https://www.ncbi.nlm.nih.gov/pubmed/29872037
http://dx.doi.org/10.1038/s41467-018-04527-8

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