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Effects of Simultaneous Downregulation of PHD1 and Keap1 on Prevention and Reversal of Liver Fibrosis in Mice

Background and Aim: To investigate whether double-knockdown of PHD1 and Keap1 in mice could enhance the resolution of carbon tetrachloride (CCl(4))-induced liver fibrosis. Methods: The liver fibrosis model of mice was established by intraperitoneal injection of 25% CCl(4) in olive oil (4 ul/g) twice...

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Detalles Bibliográficos
Autores principales:	Liu, Jing, Li, Wencai, Limbu, Manoj H., Li, Yiping, Wang, Zhi, Cheng, Zhengyuan, Zhang, Xiaoyi, Chen, Pingsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988854/ https://www.ncbi.nlm.nih.gov/pubmed/29899699 http://dx.doi.org/10.3389/fphar.2018.00555

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