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BDNF Release and Signaling are Required for the Antidepressant Actions of GLYX-13
Conventional antidepressant medications, which act on monoaminergic systems, display significant limitations, including a time lag of weeks to months and low rates of therapeutic efficacy. GLYX-13 is a novel glutamatergic compound that acts as an NMDA modulator with glycine-like partial agonist prop...
Autores principales: | Kato, Taro, Fogaça, Manoela V., Deyama, Satoshi, Li, Xiao-Yuan, Fukumoto, Kenichi, Duman, Ronald S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988860/ https://www.ncbi.nlm.nih.gov/pubmed/29203848 http://dx.doi.org/10.1038/mp.2017.220 |
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