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Magnesium Ions Inhibit the Expression of Tumor Necrosis Factor α and the Activity of γ-Secretase in a β-Amyloid Protein-Dependent Mechanism in APP/PS1 Transgenic Mice

Alzheimer’s disease (AD) is a neurodegenerative disease characterized by cognitive impairment. The neuropathological features of AD are the aggregation of extracellular amyloid β-protein (Aβ) and tau phosphorylation. Recently, AD was found to be associated with magnesium ion (Mg(2+)) deficit and tum...

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Detalles Bibliográficos
Autores principales:	Yu, Xin, Guan, Pei-Pei, Zhu, Di, Liang, Yun-Yue, Wang, Tao, Wang, Zhan-You, Wang, Pu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988891/ https://www.ncbi.nlm.nih.gov/pubmed/29899688 http://dx.doi.org/10.3389/fnmol.2018.00172

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