Cargando…
Encephalitis induced by a newly discovered ruminant rhadinovirus in a free-living Formosan sambar deer (Rusa unicolor swinhoei)
We documented a case of a free-living Formosan sambar deer (Rusa unicolor swinhoei) infected with a newly discovered ruminant Rhadinovirus (RuRv). Non-purulent encephalitis was the primary histological lesion of the sambar deer. We conducted nested PCR to screen for herpesvirus using generic primers...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Veterinary Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989027/ https://www.ncbi.nlm.nih.gov/pubmed/29607882 http://dx.doi.org/10.1292/jvms.17-0477 |
_version_ | 1783329379603972096 |
---|---|
author | CHANG, Ai-Mei CHEN, Chen-Chih CHANG, Ching-Dong HUANG, Yen-Li KE, Guan-Ming WALTHER, Bruno Andreas |
author_facet | CHANG, Ai-Mei CHEN, Chen-Chih CHANG, Ching-Dong HUANG, Yen-Li KE, Guan-Ming WALTHER, Bruno Andreas |
author_sort | CHANG, Ai-Mei |
collection | PubMed |
description | We documented a case of a free-living Formosan sambar deer (Rusa unicolor swinhoei) infected with a newly discovered ruminant Rhadinovirus (RuRv). Non-purulent encephalitis was the primary histological lesion of the sambar deer. We conducted nested PCR to screen for herpesvirus using generic primers targeting the DNA polymerase gene. In addition, we found that DNA polymerase gene of the sambar deer RuRv was present in the macrophage distributed in the Virchow Robin space with histopathologic lesions by chromogenic in-situ hybridization (CISH). The phylogenetic analysis indicated a high similarity between the viral sequence isolated from fallow deer and our case. This result suggests the possibility of cross-species transmission from other exotic Cervidae reservoir to the Formosan sambar deer. |
format | Online Article Text |
id | pubmed-5989027 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Japanese Society of Veterinary Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-59890272018-06-08 Encephalitis induced by a newly discovered ruminant rhadinovirus in a free-living Formosan sambar deer (Rusa unicolor swinhoei) CHANG, Ai-Mei CHEN, Chen-Chih CHANG, Ching-Dong HUANG, Yen-Li KE, Guan-Ming WALTHER, Bruno Andreas J Vet Med Sci Wildlife Science We documented a case of a free-living Formosan sambar deer (Rusa unicolor swinhoei) infected with a newly discovered ruminant Rhadinovirus (RuRv). Non-purulent encephalitis was the primary histological lesion of the sambar deer. We conducted nested PCR to screen for herpesvirus using generic primers targeting the DNA polymerase gene. In addition, we found that DNA polymerase gene of the sambar deer RuRv was present in the macrophage distributed in the Virchow Robin space with histopathologic lesions by chromogenic in-situ hybridization (CISH). The phylogenetic analysis indicated a high similarity between the viral sequence isolated from fallow deer and our case. This result suggests the possibility of cross-species transmission from other exotic Cervidae reservoir to the Formosan sambar deer. The Japanese Society of Veterinary Science 2018-04-02 2018-05 /pmc/articles/PMC5989027/ /pubmed/29607882 http://dx.doi.org/10.1292/jvms.17-0477 Text en ©2018 The Japanese Society of Veterinary Science This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | Wildlife Science CHANG, Ai-Mei CHEN, Chen-Chih CHANG, Ching-Dong HUANG, Yen-Li KE, Guan-Ming WALTHER, Bruno Andreas Encephalitis induced by a newly discovered ruminant rhadinovirus in a free-living Formosan sambar deer (Rusa unicolor swinhoei) |
title | Encephalitis induced by a newly discovered ruminant rhadinovirus in a free-living Formosan sambar deer (Rusa unicolor swinhoei) |
title_full | Encephalitis induced by a newly discovered ruminant rhadinovirus in a free-living Formosan sambar deer (Rusa unicolor swinhoei) |
title_fullStr | Encephalitis induced by a newly discovered ruminant rhadinovirus in a free-living Formosan sambar deer (Rusa unicolor swinhoei) |
title_full_unstemmed | Encephalitis induced by a newly discovered ruminant rhadinovirus in a free-living Formosan sambar deer (Rusa unicolor swinhoei) |
title_short | Encephalitis induced by a newly discovered ruminant rhadinovirus in a free-living Formosan sambar deer (Rusa unicolor swinhoei) |
title_sort | encephalitis induced by a newly discovered ruminant rhadinovirus in a free-living formosan sambar deer (rusa unicolor swinhoei) |
topic | Wildlife Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989027/ https://www.ncbi.nlm.nih.gov/pubmed/29607882 http://dx.doi.org/10.1292/jvms.17-0477 |
work_keys_str_mv | AT changaimei encephalitisinducedbyanewlydiscoveredruminantrhadinovirusinafreelivingformosansambardeerrusaunicolorswinhoei AT chenchenchih encephalitisinducedbyanewlydiscoveredruminantrhadinovirusinafreelivingformosansambardeerrusaunicolorswinhoei AT changchingdong encephalitisinducedbyanewlydiscoveredruminantrhadinovirusinafreelivingformosansambardeerrusaunicolorswinhoei AT huangyenli encephalitisinducedbyanewlydiscoveredruminantrhadinovirusinafreelivingformosansambardeerrusaunicolorswinhoei AT keguanming encephalitisinducedbyanewlydiscoveredruminantrhadinovirusinafreelivingformosansambardeerrusaunicolorswinhoei AT waltherbrunoandreas encephalitisinducedbyanewlydiscoveredruminantrhadinovirusinafreelivingformosansambardeerrusaunicolorswinhoei |