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Exit from Naive Pluripotency Induces a Transient X Chromosome Inactivation-like State in Males
A hallmark of naive pluripotency is the presence of two active X chromosomes in females. It is not clear whether prevention of X chromosome inactivation (XCI) is mediated by gene networks that preserve the naive state. Here, we show that robust naive pluripotent stem cell (nPSC) self-renewal repress...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989057/ https://www.ncbi.nlm.nih.gov/pubmed/29804891 http://dx.doi.org/10.1016/j.stem.2018.05.001 |