DDX41 Recognizes RNA/DNA Retroviral Reverse Transcripts and Is Critical for In Vivo Control of Murine Leukemia Virus Infection

Host recognition of viral nucleic acids generated during infection leads to the activation of innate immune responses essential for early control of virus. Retrovirus reverse transcription creates numerous potential ligands for cytosolic host sensors that recognize foreign nucleic acids, including s...

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Detalles Bibliográficos
Autores principales: Stavrou, Spyridon, Aguilera, Alexya N., Blouch, Kristin, Ross, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989071/
https://www.ncbi.nlm.nih.gov/pubmed/29871919
http://dx.doi.org/10.1128/mBio.00923-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989071/
https://www.ncbi.nlm.nih.gov/pubmed/29871919
http://dx.doi.org/10.1128/mBio.00923-18

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