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Case Report: Pulmonary and Liver Sarcoidosis Suspected of Metastasis

Introduction: Sarcoidosis is a granulomatous disease with unknown cause that can vary from an asymptomatic condition. Almost half of the patients with sarcoidosis have no symptoms. In this article, we describe a sarcoidosis patient with lung and liver engagement; it may be confused with metastasis....

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Autores principales: Jafari, Behnam, Sabz, Gholamabas, Masnavi, Elahe, Panahi, Roghaye, Jokar, Saeid, Roozbehi, Amrollah, Hasanzadeh, Sajad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989148/
https://www.ncbi.nlm.nih.gov/pubmed/29904593
http://dx.doi.org/10.12688/f1000research.13787.2
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author Jafari, Behnam
Sabz, Gholamabas
Masnavi, Elahe
Panahi, Roghaye
Jokar, Saeid
Roozbehi, Amrollah
Hasanzadeh, Sajad
author_facet Jafari, Behnam
Sabz, Gholamabas
Masnavi, Elahe
Panahi, Roghaye
Jokar, Saeid
Roozbehi, Amrollah
Hasanzadeh, Sajad
author_sort Jafari, Behnam
collection PubMed
description Introduction: Sarcoidosis is a granulomatous disease with unknown cause that can vary from an asymptomatic condition. Almost half of the patients with sarcoidosis have no symptoms. In this article, we describe a sarcoidosis patient with lung and liver engagement; it may be confused with metastasis. Case report: A 39-year-old man, with known as hypothyroidism who had come to the emergency ward with dyspnea and coughing after exposure to detergents in a closed environment. The patient smoked for 10 years (3 pack/year). No other findings were found in clinical examinations except for wheezing in the right lung. The patient's chest radiography was shown a mass. For further investigation, spiral CT scan was performed. Large lymph nodes on the right side of the trachea, measuring about 23 mm and a mass of 70 × 77 mm in the vicinity of the right lung hilum and a hypodense nodule in the posterior part of the liver with malignancy suspicious were reported. After several biopsy results was shown chronic granulomatous inflammation, the most important differential diagnosis is tuberculosis (TB) and sarcoidosis. Sputum smear, culture, and PCR were performed for tuberculosis. Also, the level of angiotensin-converting enzyme (ACE) was measured for sarcoidosis. the results ruled out TB and shown a higher level of ACE (ACE = 88 IU/L).After diagnosis treatment started with prednisolone. Now, the patient is in the follow- up. Conclusion: In hilar lymphadenopathy of lung sarcoidosis is the importance differential diagnosis that should be considered.
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spelling pubmed-59891482018-06-13 Case Report: Pulmonary and Liver Sarcoidosis Suspected of Metastasis Jafari, Behnam Sabz, Gholamabas Masnavi, Elahe Panahi, Roghaye Jokar, Saeid Roozbehi, Amrollah Hasanzadeh, Sajad F1000Res Case Report Introduction: Sarcoidosis is a granulomatous disease with unknown cause that can vary from an asymptomatic condition. Almost half of the patients with sarcoidosis have no symptoms. In this article, we describe a sarcoidosis patient with lung and liver engagement; it may be confused with metastasis. Case report: A 39-year-old man, with known as hypothyroidism who had come to the emergency ward with dyspnea and coughing after exposure to detergents in a closed environment. The patient smoked for 10 years (3 pack/year). No other findings were found in clinical examinations except for wheezing in the right lung. The patient's chest radiography was shown a mass. For further investigation, spiral CT scan was performed. Large lymph nodes on the right side of the trachea, measuring about 23 mm and a mass of 70 × 77 mm in the vicinity of the right lung hilum and a hypodense nodule in the posterior part of the liver with malignancy suspicious were reported. After several biopsy results was shown chronic granulomatous inflammation, the most important differential diagnosis is tuberculosis (TB) and sarcoidosis. Sputum smear, culture, and PCR were performed for tuberculosis. Also, the level of angiotensin-converting enzyme (ACE) was measured for sarcoidosis. the results ruled out TB and shown a higher level of ACE (ACE = 88 IU/L).After diagnosis treatment started with prednisolone. Now, the patient is in the follow- up. Conclusion: In hilar lymphadenopathy of lung sarcoidosis is the importance differential diagnosis that should be considered. F1000 Research Limited 2018-06-04 /pmc/articles/PMC5989148/ /pubmed/29904593 http://dx.doi.org/10.12688/f1000research.13787.2 Text en Copyright: © 2018 Jafari B et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Jafari, Behnam
Sabz, Gholamabas
Masnavi, Elahe
Panahi, Roghaye
Jokar, Saeid
Roozbehi, Amrollah
Hasanzadeh, Sajad
Case Report: Pulmonary and Liver Sarcoidosis Suspected of Metastasis
title Case Report: Pulmonary and Liver Sarcoidosis Suspected of Metastasis
title_full Case Report: Pulmonary and Liver Sarcoidosis Suspected of Metastasis
title_fullStr Case Report: Pulmonary and Liver Sarcoidosis Suspected of Metastasis
title_full_unstemmed Case Report: Pulmonary and Liver Sarcoidosis Suspected of Metastasis
title_short Case Report: Pulmonary and Liver Sarcoidosis Suspected of Metastasis
title_sort case report: pulmonary and liver sarcoidosis suspected of metastasis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989148/
https://www.ncbi.nlm.nih.gov/pubmed/29904593
http://dx.doi.org/10.12688/f1000research.13787.2
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