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Proteome-wide analysis of protein abundance and turnover remodelling during oncogenic transformation of human breast epithelial cells
Background: Viral oncogenes and mutated proto-oncogenes are potent drivers of cancer malignancy. Downstream of the oncogenic trigger are alterations in protein properties that give rise to cellular transformation and the acquisition of malignant cellular phenotypes. Developments in mass spectrometry...
Autores principales: | Ly, Tony, Endo, Aki, Brenes, Alejandro, Gierlinski, Marek, Afzal, Vackar, Pawellek, Andrea, Lamond, Angus I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989152/ https://www.ncbi.nlm.nih.gov/pubmed/29904729 http://dx.doi.org/10.12688/wellcomeopenres.14392.1 |
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